"TRAF" redirects here. For the school, see
TNF receptor associated factors also known as TRAFs are a family of proteins primarily involved in the regulation of inflammation, antiviral responses and apoptosis. [1 ]
Currently, seven TRAF proteins have been characterized in
mammals: TRAF1, TRAF2, TRAF3, TRAF4, TRAF5, TRAF6 and TRAF7.
Except for TRAF7, these proteins share a relatively conserved
secondary structure, including a namesake C-terminal TRAF domain that mediates interactions with other signaling components such as the transmembrane TNF receptors and CD40.
See also [ edit ]
References [ edit ]
^ Inoue J, Ishida T, Tsukamoto N, Kobayashi N, Naito A, Azuma S, Yamamoto T (January 2000). "Tumor necrosis factor receptor-associated factor (TRAF) family: adapter proteins that mediate cytokine signaling". Exp. Cell Res. 254 (1): 14–24. doi: 10.1006/excr.1999.4733. PMID 10623461.
External links [ edit ]
Growth factor receptor-bound protein
B trdu: iter ( nrpl/ grfl/ cytl/ horl), csrc ( lgic, enzr, gprc, igsr, intg, nrpr/ grfr/ cytr), itra ( adap, gbpr, mapk), calc, lipd; path ( hedp, wntp, tgfp+ mapp, notp, jakp, fsap, hipp, tlrp)