TRIB2

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Tribbles pseudokinase 2
Identifiers
Symbols TRIB2 ; C5FW; GS3955; TRB2
External IDs OMIM609462 MGI2145021 HomoloGene41445 GeneCards: TRIB2 Gene
RNA expression pattern
PBB GE TRIB2 202478 at tn.png
PBB GE TRIB2 202479 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 28951 217410
Ensembl ENSG00000071575 ENSMUSG00000020601
UniProt Q92519 Q8K4K3
RefSeq (mRNA) NM_021643 NM_144551
RefSeq (protein) NP_067675 NP_653134
Location (UCSC) Chr 2:
12.86 – 12.88 Mb
Chr 12:
15.79 – 15.82 Mb
PubMed search [1] [2]

Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene.[1][2][3][4]


References[edit]

  1. ^ Wu M, Xu LG, Zhai Z, Shu HB (Jul 2003). "SINK is a p65-interacting negative regulator of NF-kappaB-dependent transcription". J Biol Chem 278 (29): 27072–9. doi:10.1074/jbc.M209814200. PMID 12736262. 
  2. ^ Keeshan K, He Y, Wouters BJ, Shestova O, Xu L, Sai H, Rodriguez CG, Maillard I, Tobias JW, Valk P, Carroll M, Aster JC, Delwel R, Pear WS (Nov 2006). "Tribbles homolog 2 inactivates C/EBPalpha and causes acute myelogenous leukemia". Cancer Cell 10 (5): 401–11. doi:10.1016/j.ccr.2006.09.012. PMC 2839500. PMID 17097562. 
  3. ^ Hegedus Z, Czibula A, Kiss-Toth E (Aug 2006). "Tribbles: novel regulators of cell function; evolutionary aspects". Cell Mol Life Sci 63 (14): 1632–41. doi:10.1007/s00018-006-6007-9. PMID 16715410. 
  4. ^ "Entrez Gene: TRIB2 tribbles homolog 2 (Drosophila)". 

Further reading[edit]