TRIM15

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Tripartite motif containing 15
Identifiers
Symbols TRIM15 ; RNF93; ZNF178; ZNFB7
External IDs MGI1916347 HomoloGene23819 GeneCards: TRIM15 Gene
RNA expression pattern
PBB GE TRIM15 36742 at tn.png
PBB GE TRIM15 210177 at tn.png
PBB GE TRIM15 210885 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 89870 69097
Ensembl ENSG00000137384 ENSMUSG00000050747
UniProt Q9C019 Q8R096
RefSeq (mRNA) NM_033229 NM_001024134
RefSeq (protein) NP_150232 NP_001019305
Location (UCSC) Chr 6:
30.13 – 30.14 Mb
Chr 17:
36.86 – 36.87 Mb
PubMed search [1] [2]

Tripartite motif-containing protein 15 is a protein that in humans is encoded by the TRIM15 gene.[1][2][3][4]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. Its function has not been identified. Alternate splicing of this gene results in two transcript variants encoding different isoforms.[4]

References[edit]

  1. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580. 
  2. ^ Goei VL, Parimoo S, Capossela A, Chu TW, Gruen JR (Mar 1994). "Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection". Am J Hum Genet 54 (2): 244–51. PMC 1918154. PMID 8304341. 
  3. ^ Gruen JR, Nalabolu SR, Chu TW, Bowlus C, Fan WF, Goei VL, Wei H, Sivakamasundari R, Liu Y, Xu HX, Parimoo S, Nallur G, Ajioka R, Shukla H, Bray-Ward P, Pan J, Weissman SM (Feb 1997). "A transcription map of the major histocompatibility complex (MHC) class I region". Genomics 36 (1): 70–85. doi:10.1006/geno.1996.0427. PMID 8812418. 
  4. ^ a b "Entrez Gene: TRIM15 tripartite motif-containing 15". 

Further reading[edit]