TRIM9

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Tripartite motif containing 9
Protein TRIM9 PDB 2db8.png
PDB rendering based on 2db8.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols TRIM9 ; RNF91; SPRING
External IDs OMIM606555 MGI2137354 HomoloGene9045 GeneCards: TRIM9 Gene
RNA expression pattern
PBB GE TRIM9 209859 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 114088 94090
Ensembl ENSG00000100505 ENSMUSG00000021071
UniProt Q9C026 Q8C7M3
RefSeq (mRNA) NM_015163 NM_001110202
RefSeq (protein) NP_055978 NP_001103672
Location (UCSC) Chr 14:
51.44 – 51.56 Mb
Chr 12:
70.24 – 70.35 Mb
PubMed search [1] [2]

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[1][2][3]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[3]

Interactions[edit]

TRIM9 has been shown to interact with SNAP-25.[2]

References[edit]

  1. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580. 
  2. ^ a b Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem 276 (44): 40824–33. doi:10.1074/jbc.M106141200. PMID 11524423. 
  3. ^ a b "Entrez Gene: TRIM9 tripartite motif-containing 9". 

Further reading[edit]