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Tripartite motif containing 9
Protein TRIM9 PDB 2db8.png
PDB rendering based on 2db8.
Available structures
PDB Ortholog search: PDBe, RCSB
Symbols TRIM9 ; RNF91; SPRING
External IDs OMIM606555 MGI2137354 HomoloGene9045 GeneCards: TRIM9 Gene
RNA expression pattern
PBB GE TRIM9 209859 at tn.png
More reference expression data
Species Human Mouse
Entrez 114088 94090
Ensembl ENSG00000100505 ENSMUSG00000021071
UniProt Q9C026 Q8C7M3
RefSeq (mRNA) NM_015163 NM_001110202
RefSeq (protein) NP_055978 NP_001103672
Location (UCSC) Chr 14:
51.44 – 51.56 Mb
Chr 12:
70.24 – 70.35 Mb
PubMed search [1] [2]

Tripartite motif-containing protein 9 is a protein that in humans is encoded by the TRIM9 gene.[1][2][3]

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Its function has not been identified. Alternate splicing of this gene generates two transcript variants encoding different isoforms.[3]


TRIM9 has been shown to interact with SNAP-25.[2]


  1. ^ Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L, Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci S, Pelicci PG, Ballabio A (May 2001). "The tripartite motif family identifies cell compartments". EMBO J 20 (9): 2140–51. doi:10.1093/emboj/20.9.2140. PMC 125245. PMID 11331580. 
  2. ^ a b Li Y, Chin LS, Weigel C, Li L (Oct 2001). "Spring, a novel RING finger protein that regulates synaptic vesicle exocytosis". J Biol Chem 276 (44): 40824–33. doi:10.1074/jbc.M106141200. PMID 11524423. 
  3. ^ a b "Entrez Gene: TRIM9 tripartite motif-containing 9". 

Further reading[edit]