TRIP11

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Thyroid hormone receptor interactor 11
Identifiers
Symbols TRIP11 ; ACG1A; CEV14; GMAP-210; TRIP-11; TRIP230
External IDs OMIM604505 MGI1924393 HomoloGene20897 GeneCards: TRIP11 Gene
Orthologs
Species Human Mouse
Entrez 9321 109181
Ensembl ENSG00000100815 ENSMUSG00000021188
UniProt Q15643 E9Q4A9
RefSeq (mRNA) NM_004239 NM_028446
RefSeq (protein) NP_004230 NP_082722
Location (UCSC) Chr 14:
92.43 – 92.51 Mb
Chr 12:
101.83 – 101.91 Mb
PubMed search [1] [2]

Thyroid receptor-interacting protein 11 is a protein that in humans is encoded by the TRIP11 gene.[1][2][3]

TRIP11 was first identified through its ability to interact functionally with thyroid hormone receptor-beta (THRB; MIM 190160). It has also been found in association with the Golgi apparatus and microtubules.[supplied by OMIM][3]

Interactions[edit]

TRIP11 has been shown to interact with Retinoblastoma protein[4] and Thyroid hormone receptor alpha.[4]

References[edit]

  1. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (July 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974. 
  2. ^ Abe A, Emi N, Tanimoto M, Terasaki H, Marunouchi T, Saito H (December 1997). "Fusion of the platelet-derived growth factor receptor beta to a novel gene CEV14 in acute myelogenous leukemia after clonal evolution". Blood 90 (11): 4271–7. PMID 9373237. 
  3. ^ a b "Entrez Gene: TRIP11 thyroid hormone receptor interactor 11". 
  4. ^ a b Chang, K H; Chen Y, Chen T T, Chou W H, Chen P L, Ma Y Y, Yang-Feng T L, Leng X, Tsai M J, O'Malley B W, Lee W H (August 1997). "A thyroid hormone receptor coactivator negatively regulated by the retinoblastoma protein". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 94 (17): 9040–5. doi:10.1073/pnas.94.17.9040. ISSN 0027-8424. PMC 23019. PMID 9256431. 

Further reading[edit]