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Thyroid hormone receptor interactor 12
Symbols TRIP12 ; TRIP-12; ULF
External IDs OMIM604506 MGI1309481 HomoloGene44226 GeneCards: TRIP12 Gene
RNA expression pattern
PBB GE TRIP12 201546 at tn.png
More reference expression data
Species Human Mouse
Entrez 9320 14897
Ensembl ENSG00000153827 ENSMUSG00000026219
UniProt Q14669 G5E870
RefSeq (mRNA) NM_001284214 NM_133975
RefSeq (protein) NP_001271143 NP_598736
Location (UCSC) Chr 2:
230.63 – 230.79 Mb
Chr 1:
84.72 – 84.84 Mb
PubMed search [1] [2]

Probable E3 ubiquitin-protein ligase TRIP12 is an enzyme that in humans is encoded by the TRIP12 gene.[1][2]


TRIP12 has been shown to interact with APPBP1.[3]


  1. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (Jul 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974. 
  2. ^ "Entrez Gene: TRIP12 thyroid hormone receptor interactor 12". 
  3. ^ Park, Yoon; Yoon Sungjoo Kim; Yoon Jong-Bok (Sep 2008). "TRIP12 functions as an E3 ubiquitin ligase of APP-BP1". Biochem. Biophys. Res. Commun. (United States) 374 (2): 294–8. doi:10.1016/j.bbrc.2008.07.019. PMID 18627766. 

Further reading[edit]