TSPAN2

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Tetraspanin 2
Identifiers
Symbols TSPAN2 ; NET3; TSN2; TSPAN-2
External IDs OMIM613133 MGI1917997 HomoloGene21169 GeneCards: TSPAN2 Gene
RNA expression pattern
PBB GE TSPAN2 214606 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10100 70747
Ensembl ENSG00000134198 ENSMUSG00000027858
UniProt O60636 Q922J6
RefSeq (mRNA) NM_005725 NM_001243132
RefSeq (protein) NP_005716 NP_001230061
Location (UCSC) Chr 1:
115.59 – 115.63 Mb
Chr 3:
102.73 – 102.77 Mb
PubMed search [1] [2]

Tetraspanin-2 is a protein that in humans is encoded by the TSPAN2 gene.[1][2][3]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.[3]

References[edit]

  1. ^ Todd SC, Doctor VS, Levy S (Sep 1998). "Sequences and expression of six new members of the tetraspanin/TM4SF family". Biochim Biophys Acta 1399 (1): 101–4. doi:10.1016/s0167-4781(98)00087-6. PMID 9714763. 
  2. ^ Berditchevski F (Dec 2001). "Complexes of tetraspanins with integrins: more than meets the eye". J Cell Sci 114 (Pt 23): 4143–51. PMID 11739647. 
  3. ^ a b "Entrez Gene: TSPAN2 tetraspanin 2". 

Further reading[edit]

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