TSPAN3

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Tetraspanin 3
Identifiers
Symbols TSPAN3 ; TM4-A; TM4SF8; TSPAN-3
External IDs OMIM613134 MGI1928098 HomoloGene21168 GeneCards: TSPAN3 Gene
RNA expression pattern
PBB GE TSPAN3 200972 at tn.png
PBB GE TSPAN3 200973 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 10099 56434
Ensembl ENSG00000140391 ENSMUSG00000032324
UniProt O60637 Q9QY33
RefSeq (mRNA) NM_001168412 NM_019793
RefSeq (protein) NP_001161884 NP_062767
Location (UCSC) Chr 15:
77.34 – 77.38 Mb
Chr 9:
56.14 – 56.16 Mb
PubMed search [1] [2]

Tetraspanin-3 is a protein that in humans is encoded by the TSPAN3 gene.[1]

The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The use of alternate polyadenylation sites has been found for this gene. Two alternative transcripts encoding different isoforms have been described.[1]

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