TSQ

This article is about the chemical compound. For hydroelectric plant, see Tianshengqiao Hydroelectric Plant.

TSQ
IUPAC name N-(6-Methoxy-8-quinolyl)-4-toluenesulfonamide
Identifiers
CAS number	109628-27-5
PubChem	130606
ChemSpider	115530 Y
Jmol-3D images	Image 1
SMILES O=S(=O)(c1ccc(cc1)C)Nc2cc(OC)cc3cccnc23
InChI InChI=1S/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3 Y Key: HKRNYOZJJMFDBV-UHFFFAOYSA-N Y InChI=1/C17H16N2O3S/c1-12-5-7-15(8-6-12)23(20,21)19-16-11-14(22-2)10-13-4-3-9-18-17(13)16/h3-11,19H,1-2H3 Key: HKRNYOZJJMFDBV-UHFFFAOYAJ
Properties
Molecular formula	C17H16N2O3S
Molar mass	328.39 g mol−1
Y (verify) (what is: Y/N?) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

6-Methoxy-(8-p-toluenesulfonamido)quinoline (TSQ) is one of the most efficient fluorescent stains for zinc(II). It was introduced by Russian biochemists Toroptsev and Eshchenko in the early 1970s. The popularity of TSQ as physiological stain rose after seminal works by Christopher Frederickson two decades later. TSQ forms a 2:1 (ligand-metal) complex with zinc and emits blue light upon excitation at 365 nanometers. TSQ has been extensively applied for determination of extracellular or intracellular levels of Zn²⁺ in biological systems, also to study Zn²⁺ in mossy fibers of the hippocampus.