TUSC4
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| Nitrogen permease regulator-like 2 (S. cerevisiae) | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | NPRL2; NPR2; NPR2L; TUSC4 | ||||||||||||
| External IDs | OMIM: 607072 MGI: 1914482 HomoloGene: 4771 GeneCards: NPRL2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 10641 | 56032 | |||||||||||
| Ensembl | ENSG00000114388 | ENSMUSG00000010057 | |||||||||||
| UniProt | Q8WTW4 | Q9WUE4 | |||||||||||
| RefSeq (mRNA) | NM_006545.4 | NM_018879.2 | |||||||||||
| RefSeq (protein) | NP_006536.3 | NP_061367.1 | |||||||||||
| Location (UCSC) | Chr 3: 50.38 – 50.39 Mb |
Chr 9: 107.44 – 107.45 Mb |
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| PubMed search | [1] | [2] | |||||||||||
Tumor suppressor candidate 4 is a protein that in humans is encoded by the TUSC4 gene.[1][2]
[edit] References
- ^ Lerman MI, Minna JD (Nov 2000). "The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes. The International Lung Cancer Chromosome 3p21.3 Tumor Suppressor Gene Consortium". Cancer Res 60 (21): 6116–33. PMID 11085536.
- ^ "Entrez Gene: TUSC4 tumor suppressor candidate 4". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10641.
[edit] Further reading
- Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=1847948.
- Ueda K, Kawashima H, Ohtani S, et al. (2007). "The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells.". Cancer Res. 66 (19): 9682–90. doi:10.1158/0008-5472.CAN-06-1483. PMID 17018626.
- Muzny DM, Scherer SE, Kaul R, et al. (2006). "The DNA sequence, annotation and analysis of human chromosome 3.". Nature 440 (7088): 1194–8. doi:10.1038/nature04728. PMID 16641997.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=528928.
- Li J, Wang F, Haraldson K, et al. (2004). "Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C.". Cancer Res. 64 (18): 6438–43. doi:10.1158/0008-5472.CAN-03-3869. PMID 15374952.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Ji L, Nishizaki M, Gao B, et al. (2002). "Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.". Cancer Res. 62 (9): 2715–20. PMID 11980673.
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