Talk:Antidepressant

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[edit] Wellbutrin (bupropion)

Wellbutrin (buproprion hydrochloride) is an antideppresant that's not related to any of the 3 listed classes of AD's

--MarXidad, 2002-01-17 6:30 AM EST


I thought that Welbutrin was a dopamine reuptake inhibitor, and that Serzone inhibited reuptake of both seratonin and norepinephrine.

-arteitle, 2003-05-20


[edit] Anti Depressants linked to heart risk in middle aged men, as well as brain disorders and diabetes

http://www.reuters.com/article/2011/04/02/us-heart-antidepressants-idUSTRE7312FR20110402

http://www.nybooks.com/articles/archives/2011/jun/23/epidemic-mental-illness-why/?pagination=false

http://www.nybooks.com/articles/archives/2011/jun/23/epidemic-mental-illness-why/

[edit] placebo effect

From the lede: Inert placebos can have significant antidepressant effects, and so to establish a substance as an "antidepressant" in a clinical trial it is necessary to show superior efficacy to placebo

There is no evidence provided that placebos have antidepressant effect. This would require studies comparing patients given placebo with patients who don't receive medication. Otherwise we might as well conclude that placebos cure the common cold. There's no evidence that an untreated depression will persist indefinitely, the fact that some people get better on placebo doesn't prove they work. 84.197.180.127 (talk) 02:40, 16 January 2012 (UTC)
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