Talk:Cocaine
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Cocaine was one of the Natural sciences good articles, but it has been removed from the list. There are suggestions below for improving the article to meet the good article criteria. Once these issues have been addressed, the article can be renominated. Editors may also seek a reassessment of the decision if they believe there was a mistake. | ||||||||||||||||||||||
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[edit] Small Correction
In the discussion of synthesis, the word "distereomer" is used. The correct terminology is "diastereomer". — Preceding unsigned comment added by 207.68.248.184 (talk) 02:39, 9 November 2011 (UTC)
[edit] Hallucinations and Delusions
This article makes the unsubstantiated claim that hallucinations and delusions in cocaine are mostly attributed to sleep deprivation. This quite simply is not true, any agent that increases dopaminergic activity through either reuptake inhibition, increased release, or direct agonism may cause psychotic effects by acting at D2 receptors as well as some action at D1 and D3. This can be seen by reading articles on amphetamine psychosis, the dopamine hypothesis of schizophrenia, etc. I'm a bit of a university trained expert in this area, but since I'm not going to scan my old notes or credentials just go with the articles I have posted. Fireemblem555 (talk) 22:40, 11 December 2011 (UTC)
[edit] edit request
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La Colombiana redirects here, and we have a disambiguation page for Colombiana (disambiguation), so there should be a hatnote for it. "La" is a definite article, like "The" so it means the same as "The Colombiana"
Please add:
{{redirect|La Colombiana|other uses|Colombiana (disambiguation)}}
70.24.244.248 (talk) 09:19, 22 December 2011 (UTC)
- Based on a Google search, "La Colombiana" has many meanings, and "cocaine" does not appear to be among the most popular. Accordingly I've changed the target of the La Colombiana redirect to Colombiana, a disambiguation page. Please comment if you think that's not the best solution. Cheers, Adrian J. Hunter(talk•contribs) 13:09, 22 December 2011 (UTC)
[edit] Edit request on 29 January 2012
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This is incorrect (and "diastereoisomer" is spelt incorrectly):
Formation of inactive enantiomers (cocaine has 4 chiral centres – 1R,2R,3S,5S – hence a total potential of 16 possible enantiomers and disteroisomers) plus synthetic by-products limits the yield and purity.
It should be replaced with this:
Formation of inactive diastereoisomers (cocaine has 4 chiral centres – 1R,2R,3S,5S – hence a total potential of 16 possible diasteroisomers) plus synthetic by-products limits the yield and purity.
Sources:
http://en.wikipedia.org/wiki/Diastereomer http://en.wikipedia.org/wiki/Enantiomer
86.31.73.22 (talk) 11:26, 29 January 2012 (UTC)
Not done: We can't use Wikipedia article as references. I've corrected the spelling, though. Thanks, Celestra (talk) 03:25, 30 January 2012 (UTC)
