Talk:Adrenergic storm

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New article[edit]

This is my first article to actually write for WP. I just saw the broken link, and having a bit of knowledge on the subject decided to give it a go. Originally intended on writing just a couple paragraphs, but once I started looking for references I got pretty excited. So, if anyone actually ever reads this, I'd really appreciate feedback on the article - or go ahead and change it yourself! I guess I just am not entirely sure if some of the info I have is too technical. Also, I felt that there was a disproportionate amount of info on the MAO-adrenaline connection, but it is pretty important, and, even if it weren't, it's complicated enough to justify a large paragraph. Hopefully everything else with the article is good! Mr0t1633 (talk) 19:28, 16 July 2008 (UTC)

Taser[edit]

I copied this paragraph from Adrenergic storm#Causes:

Tasers can apparently provoke adrenergic storms, likely due to the body's response to its intense electrical stimulation.[1] An adrenergic storm can be intentionally provoked by the intravenous administration of epinephrine in sufficient dose; this has been used in animals to study the phenomenon.

This is the source's only direct mention of "adrenergic storm": "In addition, an intravenous infusion of epinephrine was instituted to simulate the adrenergic storm produced by a struggling, delirious, or uncontrolled individual." This concurs with the first sentence of the lead: "An adrenergic storm is a sudden and dramatic increase in serum levels of the catecholamines adrenalin and noradrenalin (also known as epinephrine and norepinephrine respectively), with less significant increases in dopamine transmission." The Nanthakumar study cited by the source found that the epinephrine injection combined with Taser discharge could produce ventricular fibrillation in pigs, suggesting a risk to humans. I could not find a source directly linking Tasers and adrenergic storms, although this study mentions metabolic effects.

As this paragraph has been adapted into a suggested hook at Template talk:Did you know, I will boldly remove it, pending revision or new sources. The source is a good overview and will probably be useful at Taser safety issues, but I'm not sure that it is relevant here. Flatscan (talk) 03:24, 19 July 2008 (UTC)

I removed the Taser text. Flatscan (talk) 03:31, 19 July 2008 (UTC)

Thanks for your feedback and for noticing this discrepancy and taking care of it. I actually wondered about it myself before putting it into the article, as the mention was brief and, IIRC, itself unsourced, but it seemed plausible. You did the right thing though regardless of whether it's selected for DYK. Mr0t1633 (talk) 03:57, 19 July 2008 (UTC)

Thanks Flatscan; I have provided an amended hook at the suggestion page here. Hassocks5489 (tickets please!) 11:01, 19 July 2008 (UTC)

A number of pointers from somebody with medical training, though I'm not familiar enough with Wikipedia to edit the article proper: -I suggest the article include a discussion of catecholamine dump, which is a traumatically induced andrenergic storm, and that this constitute a major section. -the standardized spelling in U.S. English includes an "e" at the end of adrenaline, though this is minor -MAOI induced pressor reactions can be andrenergic, but only as a result of a drug-drug interaction. The more common interaction induced by eating certain foods is tyramine potentiation, wherein tyramine acts as an agonist at norepinephrine receptors. As it stands the article is currently incorrect. —Preceding unsigned comment added by 99.50.228.162 (talk) 15:28, 23 October 2009 (UTC)
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