Talk:African trypanosomiasis

From Wikipedia, the free encyclopedia
Jump to: navigation, search
WikiProject Africa (Rated B-class)
WikiProject icon This article is within the scope of WikiProject Africa, a collaborative effort to improve the coverage of Africa on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.
B-Class article B  This article has been rated as B-Class on the project's quality scale.
 ???  This article has not yet received a rating on the project's importance scale.
 
WikiProject Medicine / Neurology (Rated B-class, High-importance)
WikiProject icon This article is within the scope of WikiProject Medicine, which recommends that this article follow the Manual of Style for medicine-related articles and use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.
B-Class article B  This article has been rated as B-Class on the project's quality scale.
 High  This article has been rated as High-importance on the project's importance scale.
Taskforce icon
This article is supported by the Neurology task force (marked as Mid-importance).
 

External Review[edit]

The following comments from external reviewer BSW-JMH are in conjunction with the joint Wikipedia talk:WikiProject Medicine/Google Project.

Hello African trypanosomiasis writers and editors. The article has been give a Class B rating on the WikiProject Medicine quality scale. The article is, for the most part, complete and has appropriate references. As part of my review, I have made some minor changes in the text to enhance the clarity and flow of the article. Further, I have detailed some suggestions below that I hope are helpful to further enhance the scope of the article.

Introductory Section[edit]

Nicely written and a good lead into the article. I also like the image and info box. I changed the last sentence to include more specific information about the previous epidemics, using ref #3 (^ WHO Media centre (2006). Fact sheet N°259: African trypanosomiasis or sleeping sickness). This reference should be added, in addition to ref #4 (^ a b c "Uganda: Sleeping Sickness Reaching Alarming Levels," New Vision, May 11, 2008.) to the last sentence. Also Google Health has a nice page that could be added to the references here. https://health.google.com/health/ref/Sleeping+sickness

Signs and symptoms[edit]

This heading could be simplified to, "Symptoms" or be made more specific, "Disease stages and symptoms". I smoothed out the text in this section a bit, just to make it easier to read. However, some citation is needed for the main section dealing with symptoms and disease progression. The Winterbottom's sign article does not have an image, so an image added to that page and/or to this page would be quite dramatic. These is some discussion about whether peer-reviewed journal articles should be used as citations, since many of these articles would not be available to the general public; however, for references 5 and 6 (^ Olowe SA (1975). "A case of congenital trypanosomiasis in Lagos". Trans. R. Soc. Trop. Med. Hyg. 69 (1): 57–9. doi:10.1016/0035-9203(75)90011-5. PMID 1170654. ^ Rocha G, Martins A, Gama G, Brandão F, Atouguia J (January 2004). "Possible cases of sexual and congenital transmission of sleeping sickness". Lancet 363 (9404): 247. doi:10.1016/S0140-6736(03)15345-7. PMID 14738812. ), given that these cite specific types of transmission, I like that the supporting information is included.

Trypanosome life cycle[edit]

Minor changes were made to smooth out the text. A link to the Trypanosome article could be included here.

Diagnosis[edit]

The text here was simplifed and technical words/phrases were replaced with common language and the section was rearranged a little to improve flow.

Other suggestions: The figure legend is very technical and should be simplified. Description of the trypanosome form should be replaced with a link to the Trypanosome article.

Some detail about what/why Giesma is used to stain smears.

The details on preparing the slides could be made into a seperate section and more detail on this given. This does not directly pertain to diagnosis, but rather microbiology methods to detect trypanosomes in samples. A seperate section would enable persons interested in detailed methods to find the information and allow those who do not need this information to easily skip it.

Information about the manufacturers of the serological tests would be useful.

Prevention[edit]

This section was revised for clarity. Suggestion: a more detailed explanation of the insecticies and methods to reduce the tsetse fly population would be a nice addition. Is the term "gambinese disease" clear, or should it be changed to "infection with T. gambinese..." If there are references to specific groups that do community-based screening, it would be good to have an external reference to this.

Treatment[edit]

Here are a few suggestions that might be useful to enhance this section.

Simplify the alternatives and make it more clear that both Eflornithine and melarsoprol are alternative drugs that are no longer or rarely used. Perhaps a short description of why administration of these drugs is so labor intensive.

If possible, place external links to the manufacturer of these drugs. References 6 and 10 are contradictory.

Epidemology[edit]

Minor changes were made. The following sentence is out of place in this section. Can it be moved to another section or a seperate paragraph be made and this idea expanded upon. According to recent estimates, the disability adjusted life years (9 to 10 years) (DALYs) lost due to sleeping sickness are 2.0 million.[1]

History[edit]

This section was well written; however, citations are needed throughout this section. Also, this is primarily a history of treatments for sleeping sickness. This would be a good section to detail information about the epidemics. Also, this section should be moved to earlier in the article.

Research[edit]

Minor changes were made. New developments should be added as necessary Norkela Was Here!..............Ily Babez!!!!!!!!!!!!!!!!!!!!!!!!!!!!Li'Phat!!!!!!!!!!!!!!!!!!!!!!!!!!!!$GMB$!!!!!!!!!!!!!!!!!!!!

Norkela Words Babe Li'Phat!!!!!!!!!<3Ily<3

Norkela Words Babe Li'Phat!!!!!!!!!<3Ily<3

External links[edit]

The CDC and WHO has several pages that would be useful links. http://www.cdc.gov/ncidod/dpd/parasites/trypanosomiasis/default.htm http://apps.who.int/tdr/svc/diseases/african-trypanosomiasis —Preceding unsigned comment added by BSW-JMH (talkcontribs) 04:23, 20 May 2010 (UTC) Overall this article looks good. Addition of a little more detail to these sections and reducing the jargon and technical language should help improve the article's grade. BSW-JMH (talk) 04:08, 20 May 2010 (UTC)

Sections[edit]

Should section headings such as epidemiolgy and treatment be added to this article? --McDogm 15:04, 7 September 2005 (UTC)

I, like, totally think so, Sugar!-Marrymary888

Definitely, I thinkk that everybody should be able to learn all about bad things like this. We all should be prepared for the rough breaks in life. -Krista-

Timeline[edit]

What's the typical timeline, from infection to neurological phase to death? --Itinerant1 (talk) 09:14, 19 July 2008 (UTC)

Geographic distribution and epidemiology[edit]

Is it possible that the graphic of the map is not correct? If I understand the data linked there ([1]) correctly the maximum death rate by trypanosomiasis is rather 16 than 160.

Do I understand the data wrong or is there a mistake in the picture? —Preceding unsigned comment added by 80.142.191.15 (talk) 18:24, 3 November 2009 (UTC)

  1. ^ World Health Organization (Geneva) (2000). World Health Report 2000: Health Systems Improving Performance.