Talk:Anti-neutrophil cytoplasmic antibody

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According to the kumar and clark 2006 edition "clinical medicine" the use of c and p ANCA is outdated. can anyone confirm/correct this?

The terms C & P ANCA remain in routine clinical use by vasculitis specialistsMalittle (talk) 18:53, 29 May 2008 (UTC)


Correct name[edit]

The correct name is Anti-neutrophil cytoplasmic autoantibody! See Kumar editions... NCurse work 09:12, 1 July 2006 (UTC)

  • Most journal articles use anti-neutrophil cytoplasmic antibody, or a variation on the theme... Autoantibody implies that the antibody is raised against self-antigens, but I don't feel the distiction is really too necessary! PMJ 21:02, 2 December 2006 (UTC)

Redirects and the like[edit]

I personally (with my vested interest...) feel that ANCA should link to Anti-neutrophil cytoplasmic antibody and not ANCA Pty Ltd, the Australian company. I propose to move ANCA to ANCA (company), a per the manual of style, and update the disambiguation page - then redirect ANCA to Anti-neutrophil cytoplasmic antibody. PMJ 21:02, 2 December 2006 (UTC)

Well, no-one disagreed so I've been bold and now it's done... PMJ 21:32, 26 December 2006 (UTC)

Images[edit]

I'll try and get some photos of cytoplasmic and perinuclear staining. I know I've got some TGN and lamp pics somewhere... PMJ 21:37, 26 December 2006 (UTC)

User: Beetstra has removed my external link as he has stated it does not follow Wikipedia guidelines. Wikipedia guidelines state that: "Wikipedia articles can include links to Web pages outside Wikipedia. Such pages could contain further research that is accurate and on-topic; information that could not be added to the article for reasons such as copyright or amount of detail (such as professional athlete statistics, movie or television credits, interview transcripts, or online textbooks); or other meaningful, relevant content that is not suitable for inclusion in an article (such as reviews and interviews)".

I believe that information found at the UNC Kidney Center on ANCA disease is beneficial to Wiki readers as it relates ANCA vasculitis in a "patient-friendly" way. Please feel free to visit and see for yourself: http://unckidneycenter.org/patients/anca_vasculitis.htm. I would appreciate any feedback.

--Unckc 21:56, 5 April 2007 (UTC)Unckc

Verifiability[edit]

I could not find decent sources for the following two items:

  • ANCA that develop against antigens other than MPO or PR3 will occasionally result in patchy staining when visualized by immunofluorescence, and most commonly occurs in patients with non-vasculitic diseases that are associated with ANCA formation. This pattern is commonly called the 'snowdrift' pattern.
  • A third distinct ANCA, x-ANCA, may be seen in many disease processes, but is most commonly found in chronic inflammatory bowel disease.[1]

Will ping an experienced editor to ask for his input. JFW | T@lk 18:29, 24 September 2012 (UTC)

Wegner's granulomatosis[edit]

I have changed Wegner's granulomatosis to granulomatosis with polyangiitis as per the more recent name change of the disease. In both mentions of the disease I have said (previously known as Wegener's granulomatosis). Simon Caulton (talk) 20:53, 27 September 2012 (UTC)
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