|This article is of interest to the following WikiProjects:|
|This article has an assessment summary page.|
An autosomal dominant gene is one on an autosome and is always expressed, even if a single copy exists. The chance is 1:2 for passing this gene to offspring.
Surely the second sentence above is incorrect? Unless something funny happens during recombination, the author has got phenotypes mixed up with genotypes - if the parent in question is heterozygous then there is a 50% chance the gene passed on from that parent is passed to the offspring.
You're right--and I think the last two sentences should be deleted. It looks like it's giving an example of how one would use the word "autosomal," so the second and third sentences, be they correct or not (and the second is not correct) are irrelevant. --ClarkFreifeld 21:45, 19 January 2006 (UTC)
Scientific literature usually refers to sex chromosomes as allosomes, heteromorphic sex chromosomes, or heterosomes. Online (English language) dictionary definitions of gonosome have nothing to do with chromosomes at all, so I replaced it.
Chondrite 07:12, 7 September 2006 (UTC)
Shouldn't there be some information of the different autosomal groups, just as mtDNA and Y & X STRs have different haplogroups? I know there are different markers for autosomes, so I think wikipedia should have at least some information on the different major markers and their associated frequencies within certain populations; just as the haplogroup pages have done for mtDNA and the Y STRs. Nagelfar 02:31, 31 December 2006 (UTC)
- Added CODIS markers and some links that might help with the above endeavor. Nagelfar 23:36, 1 March 2007 (UTC)
- Y chromosomes and mitochondrial DNA are reproduced one for one, but, even if the integrity of autosomal chromosomes was preserved, you would have a twenty something dimensional space, involving contributions from both parents. However, the germ cell line actually undergoes genetic recombination, so the level of mix and match is even greater.
- As to markers, there are many markers documented in Wikipedia, e.g. see autosomal recessive disorders. Details of benign autosomal alleles are likely to be commercially confidential.
- -- David Woolley (talk) 16:56, 26 October 2008 (UTC)
Excessive Genealogy Bias
A big flaw in this article seems to be that it has been written as though geneology, based on benign alleles, is the main area in which autosomes are of interest, when the actual main area of interest is the study of genetic diseases. That seems to reflect a pop science versus hard science bias. David Woolley (talk) 17:01, 26 October 2008 (UTC)
Should the page "autosome" contain a redirect from "autosomal"? i noticed that many pages with the word autosomal link to this yet no redirect exists. I also noticed that i can't make redirects. How can i go about getting this changed, is it possible? Jsorr (talk) 13:51, 8 March 2009 (UTC)