Talk:Clostridium botulinum

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Ability to kill the spores?[edit]

The following paragraph appears in the text. It is ended by a "NOT!" reminiscent of Borat. Such an expression is not appropriate for a scientific article such as this one. Although I am not an expert on the subject, I also believe I read somewhere that it wasn't possible to kill the spores of the botulinum by pressurized boiling. Can anybody confirm this? watevrrrr

Clostridium botulinum is a soil bacterium. The spores can survive in most environments and are very hard to kill. They can survive the temperature of boiling water at sea level, thus many foods are canned with a pressurized boil that achieves an even higher temperature, sufficient to kill the spores.NOT!

Genome sequenced.[edit]

See Sanger or say New Scientist blurb etc. Needs to be mixed into article when people have time. Ttiotsw 15:05, 28 May 2007 (UTC) i hate you!!11 —Preceding unsigned comment added by 72.10.103.193 (talk) 18:45, 10 November 2009 (UTC)

They are anaerobic[edit]

"These rod-shaped organisms grow best in low-oxygen conditions." They are anaerobic. Not only facultatively. This sentence above can mislead the reader, because it suggests that they still grow even under high-oxygen conditions... Low oxygen conditions can be TOLERATED by them, which means something totally different. They are able to SURVIVE the presence of oxygen, because they have an enzyme called SOD (superoxide dismutase). Oxygen however is not something they like, it's actually quite toxic for them. Myrmeleon formicarius (talk) 20:18, 11 January 2008 (UTC)

Just to add some more sources than my own silly head: "Clostridium Facts Clostridium perfringens is a Gram-positive anaerobic spore-forming bacterium" I didn't have to go further for this sentence than the link at the external links of the article...

http://pathema.tigr.org/tigr-scripts/Clostridium/PathemaHomePage.cgi

This article should be improved... Myrmeleon formicarius (talk) 20:47, 11 January 2008 (UTC)

Would the presence of SOD make them aerotolerant? —Preceding unsigned comment added by 24.182.41.227 (talk) 01:53, 2 April 2010 (UTC)

:D I'm happy to see[edit]

PROGRESS!!! You are great, thanks for improving the article :) Myrmeleon formicarius (talk) 02:50, 18 January 2009 (UTC)

Infant[edit]

As soon as infants begin eating solid food, the digestive juices become too acidic for the bacterium to grow.

Does this mean babies can die from being fed toxin free spores? Jokem (talk) 20:44, 7 July 2009 (UTC)

Infant botulism happens when the bacteria colonize the intestines of an infant, which lack the flora of an adult. It just has to survive the stomach acid, not grow in it. I don't know for sure with infant botulism but in cholera the bacteria are aided in their survival and eventual colonization of the intestines by protection from stomach acid by food and Vibrio cholerae is highly susceptible to acid. Thus, spores consumed without botulism toxin can cause a botulism disease. I believe it is the same deal with wound botulism.WillWritesWiki (talk) 19:27, 3 January 2010 (UTC)

LD50[edit]

According to the page for Botulinum toxin, the LD50 is 5 to 50 ng/kg, not 1 ng/kg. Which is correct? Hieronymus Illinensis (talk) 00:26, 27 January 2010 (UTC)