Talk:Corticotropin-releasing hormone

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I am rather sure that "corticotrophin" is misspelt. -trop- = "directed at", -troph- = related to nourishment or growth. "Corticotropin" = ACTH = Adrenocorticotropic (not trophic) Hormone, as it's directed at the adernal cortex. Kosebamse 17:00, 4 Nov 2003 (UTC)

This has been one of my bugaboos too. But actually, both -tropin and -trophin are correct (and in common usage), since the releasing hormones have both tropic and trophic effects (the latter referring to releasing hormones promoting the growth of their target anterior pituitary cells). However, I agree with you that -tropic is preferred; most assays for releasing hormones measure their tropic rather than trophic effects. That goes for the -trophs or -tropes of the anterior pituitary as well; for example, gonadotropes is preferred over gonadotrophs. --David Iberri (talk) 16:18, 2 April 2006 (UTC)


The use of the phrase suicide "victim" seems to sacrifice accuracy for mistaken political correctness.Venadune (talk) 19:01, 14 March 2008 (UTC) —Preceding unsigned comment added by Venadune (talkcontribs) 18:57, 14 March 2008 (UTC)

PVN could do with a hyperlink —Preceding unsigned comment added by 129.31.104.167 (talk) 15:55, 28 March 2008 (UTC)

Is there any CRH found or produced in skin?[edit]

To the main editors of this article:

At the end of the following scientific news it is claimed that "it is known that the stress-hormone CRF, its receptors and other peptides that modulate these receptors are found in human skin." Could anyone with some expertise in the field verify and add some text to the article if the assertion above is true? Many thanks.

Regrowing hair: UCLA-VA researchers may have accidentally discovered a solution

Pmronchi (talk) 13:42, 18 February 2011 (UTC)

Skin does not produce CRF. CRF stimulates the synthesis of ACTH which stimulates the synthesis of cortisol. Glucocorticoids are hormones involved in many diseases (baldness, diabetes, hypertension, osteoporosis, depression, colitis, erectile disfunction etc), therefore reducing the synthesis of cortisol you can reduce the baldness as well. —Preceding unsigned comment added by 85.207.153.250 (talk) 20:26, 28 February 2011 (UTC)

Research linked to reversing alopecia[edit]

This might be a good addition to the article, research from Dr. Mulugeta Million of UCLA: http://abcnews.go.com/Health/Wellness/baldness-alopecia-reversed-mice/story?id=12932070 -Legaia (talk) 18:57, 23 January 2013 (UTC)

Actually, from Baldness, I found a better source: http://www.plosone.org/article/info:doi/10.1371/journal.pone.0016377 -Legaia (talk) 19:00, 23 January 2013 (UTC)

CRF may be link between exercise and less Alzheimers[edit]

See Exercise can slow onset of alzheimers and its link to the research article. - Rod57 (talk) 20:18, 26 January 2013 (UTC)