Talk:FCAR

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Wiki Education Foundation-supported course assignment[edit]

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Immcarle33.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 21:05, 16 January 2022 (UTC)[reply]

Assessment comment[edit]

The comment(s) below were originally left at Talk:FCAR/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

Much more could be written on this subject covering the molecular aspects of ligand interactions, signaling and effector functions. The references cited although appropriate are mainly older papers and do not adequately reflect progress in the field in recent years. A thorough treatment of this topic like that described in Dr. van de Winkel's Annual Review article would be a welcome addition. CD89fan

Last edited at 14:43, 6 July 2008 (UTC). Substituted at 14:53, 29 April 2016 (UTC)

Proposed Bibliography[edit]

These are some of the sources I've compiled that I will work from in the coming weeks to edit this page:

Bakema, J. E., and M. Van Egmond. "The human immunoglobulin A Fc receptor FcαRI: a multifaceted regulator of mucosal immunity." Mucosal immunology 4.6 (2011): 612-624.

Aleyd, Esil, Marieke H. Heineke, and Marjolein Egmond. "The era of the immunoglobulin A Fc receptor FcαRI; its function and potential as target in disease." Immunological reviews 268.1 (2015): 123-138.

Papista, Christina, et al. "Gluten exacerbates IgA nephropathy in humanized mice through gliadin–CD89 interaction." Kidney international 88.2 (2015): 276-285.

Mkaddem, Sanae Ben, et al. "Anti-inflammatory role of the IgA Fc receptor (CD89): from autoimmunity to therapeutic perspectives." Autoimmunity reviews 12.6 (2013): 666-669.

Tissandié, Emilie, et al. "Both IgA nephropathy and alcoholic cirrhosis feature abnormally glycosylated IgA1 and soluble CD89–IgA and IgG–IgA complexes: common mechanisms for distinct diseases." Kidney international 80.12 (2011): 1352-1363.

Wu, Jianming, et al. "FcαRI (CD89) alleles determine the proinflammatory potential of serum IgA." The Journal of Immunology 178.6 (2007): 3973-3982. Smith, Phillip D., et al. "Intestinal macrophages lack CD14 and CD89 and consequently are down-regulated for LPS-and IgA-mediated activities." The Journal of Immunology 167.5 (2001): 2651-2656.

Kanamaru, Yutaka, et al. "Inhibitory ITAM signaling by FcαRI-FcRγ chain controls multiple activating responses and prevents renal inflammation." The Journal of Immunology 180.4 (2008): 2669-2678.

-- Immcarle33 (talk) 06:48, 8 February 2017 (UTC)[reply]