Talk:Familial Mediterranean fever

From Wikipedia, the free encyclopedia
Jump to: navigation, search
WikiProject Medicine / Dermatology / Medical genetics (Rated C-class, Mid-importance)
WikiProject icon This article is within the scope of WikiProject Medicine, which recommends that this article follow the Manual of Style for medicine-related articles and use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.
C-Class article C  This article has been rated as C-Class on the project's quality scale.
 Mid  This article has been rated as Mid-importance on the project's importance scale.
Taskforce icon
This article is supported by the Dermatology task force.
Taskforce icon
This article is supported by the Medical genetics task force.
 

With regard to ethnic indicators, the cited article is not the best one, and the current description is misleading. Recent research suggests that Ashkenazi Jews are, in fact, carriers of FMF at the rate of approximately 20 percent. See "Mutation and Haplotype Studies of Familial Mediterranean Fever Reveal New Ancestral Relationships and Evidence for a High Carrier Frequency with Reduced Penetrance in the Ashkenazi Jewish Population", Am. J. Hum. Genet. 64:949–962, 1999, <http://www.journals.uchicago.edu/AJHG/journal/issues/v64n4/980834/980834.web.pdf>.

Metaraminol Provocative Test (MPT[edit]

I have not found this recommended in any of the current literature. Ben-Chetrit et al have presented contradictory findings in 1990 in a letter to the editor (Lancet)[1]. There does not seem to have been much discussion on the subject since.

Anakinra[edit]

Ann Intern Med this week - Anakinra helps if colchicine fails or is poorly tolerated. JFW | T@lk 22:37, 4 June 2007 (UTC)

Or rilonacept doi:10.7326/0003-4819-157-8-201210160-00003. Same journal incidentally. JFW | T@lk 23:20, 17 February 2014 (UTC)

Review[edit]

doi:10.1111/j.1365-2141.2009.07733.x - Br J Haematol JFW | T@lk 19:40, 12 August 2009 (UTC)

  1. ^ (Ben-Chetrit, Eldad; Gutman, Alisa; Levy, Micha (1990). "Dopamine-β-hydroxylase activity in familial Mediterranean fever". The Lancet 335 (8682): 176–176. doi:10.1016/0140-6736(90)90055-A. ISSN 0140-6736.