Talk:Fibroblast

From Wikipedia, the free encyclopedia
Jump to: navigation, search
          This article is of interest to the following WikiProjects:
WikiProject Physiology (Rated Mid-importance)
WikiProject icon This article is within the scope of WikiProject Physiology, a collaborative effort to improve the coverage of Physiology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.
 ???  This article has not yet received a rating on the quality scale.
 Mid  This article has been rated as Mid-importance on the importance scale.
Taskforce icon
This article has been classified as relating to the physiology of cells.
 
WikiProject Molecular and Cellular Biology (Rated Start-class, Mid-importance)
WikiProject icon This article is within the scope of the WikiProject Molecular and Cellular Biology. To participate, visit the WikiProject for more information.
Start-Class article Start  This article has been rated as Start-Class on the project's quality scale.
 Mid  This article has been rated as Mid-importance on the project's importance scale.
 
WikiProject Medicine (Rated Start-class, Low-importance)
WikiProject icon This article is within the scope of WikiProject Medicine, which recommends that this article follow the Manual of Style for medicine-related articles and use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.
Start-Class article Start  This article has been rated as Start-Class on the project's quality scale.
 Low  This article has been rated as Low-importance on the project's importance scale.
 

BJ fibroblasts[edit]

The BJ line of fibroblasts is just a standard cell line. There are more than a dozen lines of human fibroblasts readily available to the researcher. The fact that it was derived from foreskin is not especially important, and fibroblast cells in a normal human male's foreskin are not "BJ" fibroblasts; they're just plain fibroblasts.

The name, since it seems to interest you, derives (like most cell lines) from the original source, which is Baylor College of Medicine (JR Smith's lab, to be precise).

If you think that a table of information about the most popular fibroblast cell lines (and this is one of them) will interest the general reader, then please feel free to find the appropriate references and assemble the information. Until then, let's leave this out of the article. WhatamIdoing (talk) 23:44, 20 November 2008 (UTC)

Unclear sentence[edit]

"This remarkable behavior may lead to discomfort in the rare event that they stagnate there excessively." I think this sentence is very unclear and I have no idea what it actually is supposed to mean. Why would anyone want to transplant fibroblasts in human?! And "Stagnate excessively" is like saying "doing nothing, in exccess". Leading to "discomfort", aha. — Preceding unsigned comment added by 134.160.83.73 (talk) 06:21, 1 December 2011 (UTC)

External link not working[edit]

As of now, I get a "Not Found" reply from:

fibroblast at eMedicine Dictionary

that I see in my browser as: http://www.emedicine.com/asp/dictionary.asp?keyword=fibroblasts --Fioravante Patrone en (talk) 10:27, 13 March 2009 (UTC)

Keratocytes[edit]

Do keratocytes (corneal fibroblasts) merit a separate page or should they be included in this article as a subsection? --CopperKettle 10:31, 5 May 2009 (UTC)

Fibroblasts in cancer research[edit]

Perhaps a little side note for those who are interested. In many different cancer research projects, human fibroblasts are used due to their easy access and easy cultivation. Many discoveries have been made using these fibroblasts as a model for the development of cancer cell-lines. The important down-side of using fibroblasts as a model for cancer research is of course that humans in vivo hardly ever get cancer in their fibroblasts. If ever.

I am not entirely sure why stem cells (from adults, which to my understanding makes it completely legal) are not used in a lot of cancer research. I can only speculate stem cells are more difficult to attain and/or cultivate. Or financial reasons, of course. Redtails (talk) 13:52, 14 January 2011 (UTC)

size/scale bar on image[edit]

Would be nice to mention magnitude of width of fibroblast / to have a scale bar on the image.

173.206.212.150 (talk) 04:51, 8 February 2011 (UTC)

ectopic fibroblasts[edit]

If fibroblasts have diverse appearances based on location and activity, would it not be easy to tell the if they are ectopic? Would they be morphologically inconspicuous?(referring to the second paragraph in the background information).

Melissa.k.d (talk) 18:35, 11 March 2011 (UTC)