Talk:G protein

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Cleanup attempt[edit]

I tried to clean up this article a bit, but I really couldn't figure out what the original author was saying in the last paragraph. I'm also not sure what Greek letter he/she meant to put in with that last little rectangle. If I get a chance in the next few days, I'll try to re-write that last paragraph, but anyone reading this should feel free to do it themselves if they feel up to it. I'm also not sure what we should do about the small G protiens. Is the link to small GTPase enough? Also, check out GTPase and see if there's too much overlap.

To Sayeth[edit]

Just wanna say that you've done a great job re-editing this page already.
I can't figure out that rectangle, either. I guess this means I should hit the books ..... :-)
-- PFHLai 22:36, 2004 May 25 (UTC)


I don't understand why Jiang would label this G protein page "clean enough". The last paragraph is not fixed yet, and there is still too little info on the beta and gamma subunits ....  ?????? -- PFHLai 00:25, 2004 May 26 (UTC)


For the record, Sayeth has fixed this page, and it's indeed "clean enough" now. Maybe Jiang is psychic or sth .....  :-)
-- PFHLai 15:34, 2004 Jun 6 (UTC)


Of course Jiang is psychic, he's a super-wikipedian! -- Sayeth 16:38, 8 Jun 2004 (UTC)


GDP stands for Guanosine_diphosphate. Is this guanine diphosphate then equally correct? I assume not, therefore I changed it. WouterVH 15:08, 6 May 2005 (UTC)


The part about "When a ligand activates the G-protein coupled receptor, the G-protein binds to the receptor, releases its bound GDP from the Gα subunit, and binds a new molecule of GTP." is a little conusing under Receptor-activated G-proteins. Could someone clear it up?--Dan 02:10, 21 January 2006 (UTC)

Possible Copyvio[edit]

These two edits [1] [2] may be a copyright violations. The editor will only divulge that the source is "online" and has made numerous similar edits that are copyright violations. I propose removing all of what remains from those edits: the Introduction, Serpentine Receptors, and G protein–coupled receptors Sections. --Ronz 16:45, 19 October 2006 (UTC)

  • I think you should give it a week and if the sources aren't found, then remove them. These sections can be easily re-written and sourced; G-proteins are well known to most molecular/cell biologists, so I don't think it will be hard to find contributors to this page. --MPW 21:34, 20 October 2006 (UTC)
Agreed. If I could find the source and knew it was a copyvio, I would be more inclined to get rid of it quicker. --Ronz 00:46, 21 October 2006 (UTC)
I removed the information in question November 20. --Ronz 02:47, 9 December 2006 (UTC)

incomplete article[edit]

Need to include info on Gs, Gi.

  • control mechanisms of GTP and GDP — Preceding unsigned comment added by 72.240.59.98 (talk) 23:12, 19 November 2011 (UTC)
  • beta-adrenergic receptors are Gs: cAMP up (A-cyclase stimulated), stimulation of metabolism, stimulation of heart rate

smooth muscle relaxation in certain blood vessels

  • alpha2-adrenergic receptors are Gi: cAMP down (A-cyclase inhibited)
  • alpha1-adrenergic receptors are G: hydrolyze PIP2 to IP3 and DAG

alpha adrenergic receptors functions: smooth muscle contraction in other blood vessels 129.31.72.52 10:08, 12 June 2007 (UTC)

Language[edit]

Isn't this article suppose to be ENGLISH?  :Fixed. 151.61.151.235 (talk) 17:02, 2 May 2011 (UTC)

Proposed merger with G protein-coupled receptor[edit]

The following discussion is closed. Please do not modify it. Subsequent comments should be made in a new section. A summary of the conclusions reached follows.
Closing discussion due to discussion being placed on the wrong page per WP:MERGE. For the most recent proposal, please go here. Thank you. Steel1943 (talk) 17:22, 4 August 2012 (UTC)

Should this be merged with G_protein-coupled_receptor maybe with a redirect?doctorwolfie (talk) 13:12, 23 September 2010 (UTC)

Favor – G proteins have one major function- that in G protein-coupled receptors User:Jbachna (talk) 18:21, 19 November 2011 (UTC)
This merger proposal was not entered in a manner on Wikipedia that could be opened up for a proper discussion ... fixing this issue by adding templates to both articles, and fixing the title of this section. In addition, per WP:MERGE, this discussion should have been placed on Talk:G protein-coupled receptor; starting a new discussion on that article. Steel1943 (talk) 17:02, 4 August 2012 (UTC)

The above discussion is preserved as an archive. Please do not modify it. Subsequent comments should be made in a new section.


hormone full names/links[edit]

Would it be posible to add full names or links of hormones in the Specific mechanisms section? I don't know what is LH for example, and its hard to google it from just two letters long abbreviation. --78.80.8.197 (talk) 19:03, 16 January 2012 (UTC)

Merger Proposal with Heterotrimeric G protein[edit]

The following discussion is closed. Please do not modify it. Subsequent comments should be made in a new section. A summary of the conclusions reached follows.
Closing discussion for new merger proposal into G protein-coupled receptor. Steel1943 (talk) 17:19, 4 August 2012 (UTC)

In June 2011, Heterotrimeric G protein was recommended to be merged into G protein, but the discussion was not properly started. I am not an expert in this field, but from what it looks like from what I see, it looks like the two articles refer to similar topics. Should these two articles be merged? Steel1943 (talk) 16:57, 4 August 2012 (UTC)

Closing discussion for new merger proposal. Steel1943 (talk) 17:19, 4 August 2012 (UTC)

The above discussion is preserved as an archive. Please do not modify it. Subsequent comments should be made in a new section.