Talk:Gastroparesis

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Gardasil?![edit]

Removed claim that Gardasil causes gastroparesis. Citations were from "truthaboutgardasil.org" (which was itself un-referenced, and obviously has an axe to grind) and an article based entirely on inappropriate and unscientific use of the VAERS databases. Jeshyr (talk) 13:18, 15 November 2013 (UTC)

A Mess[edit]

Constructive criticism: The article is a mess (one un-punctuated sentence ends in garbled letters) and would do well with someone fact checking and grammar correcting. I would do it but I know next to nothing about this topic. I did fix it so certain text doesn't scroll endlessly off to the right. — Preceding unsigned comment added by 07:05, 3 October 2012 (UTC)

The problems may have been fixed now but I'm not seeing problems with poor grammar. Should the copy-edit needed tag be removed now? Fireflo (talk) 10:01, 18 October 2012 (UTC)

Botox[edit]

Botox into the pylorus does not improve gastroparesis compared to placebo: doi:10.1111/j.1365-2036.2007.03467.x JFW | T@lk 11:39, 19 October 2007 (UTC)

Scintigraphy[edit]

Consensus on scintigraphy for gastric emptying studies doi:10.1111/j.1572-0241.2007.01636.x JFW | T@lk 22:53, 22 November 2007 (UTC)

Epidemiology[edit]

doi:10.1111/j.1572-0241.2007.01658.x more admissions over the years, suggesting increase in occurrence. JFW | T@lk 15:20, 2 December 2007 (UTC)

Review[edit]

Aliment Pharm Ther review doi:10.1111/j.1365-2036.2007.03534.x JFW | T@lk 07:21, 9 December 2007 (UTC)

No idea why that DOI doesn't work. Blackwell are a bit slow in reporting DOIs to the DX server, methinks. Anycase, here is another review Epstein et al. JFW | T@lk 23:48, 4 February 2008 (UTC)

Another review (2014): doi:10.1136/gutjnl-2013-306084 JFW | T@lk 14:57, 31 October 2014 (UTC)

Relationship to achlorhydria?[edit]

Is there much of a relationship between this and achlorhydria? I would think that there might be a relationship as the body might not want to empty the contents of the stomach until they are properly digested, which could be delayed by a less acidic environment. However, I've not been able to find much information connecting these two things. A paragraph in Delayed Gastric Emptying and Gastric Autoimmunity in Type 1 Diabetes seems to discuss this issue:

Cyclic variation in gastric acid secretion, synchronous with the various phases of the migrating motor complex, have been shown in duodenal ulcer disease (21). Moreover, one group observed a delay in gastric emptying in patients with chronic atrophic gastritis and hypo- or achlorhydria (20). However, others have reported that interdigestive antroduodenal motility in achlorhydria is not different from that in normal acid-secreting control subjects (21). Our results support the observation that acid secretion is not essential in the regulation of gastric motility (47). Moreover, we did not observe a link between gastric motility and PCA positivity, the latter being associated with hypochlorhydria, or gastric histology. Furthermore, HP infection did not influence gastric emptying or the presence or severity of gastrointestinal symptoms (22). This is an important observation, because abnormal gastric emptying could affect urea breath test results. We and others have found no association between urea breath test and gastric emptying breath test results (22).

This little paragraph suggests that there's not much of a relationship, I guess? This article Interdigestive antroduodenal motility and gastric acid secretion is a bit more focused and says the same thing. Yet I wonder how that can be, and whether these findings reflect the long-term effect. Wouldn't the stomach want to slow down its emptying to more fully digest things when there's less digestion happening? In contrast, this article http://www.springerlink.com/content/g7858052634325vw/ Gastric Emptying and Dyspeptic Symptoms in Patients with Nonautoimmune Fundic Atrophic Gastritis] seemingly found a bit of a correlation between gastric delays and reduced acid.

Interestingly, the next sentence says "Despite the fact that all patients were euthyroidic, we observed a strong correlation between t1/2breathliquid and TSH levels. Thus subclinical hypothyroidism may affect gastric motor activity..." II | (t - c) 01:48, 7 November 2010 (UTC)