Talk:Hypertrophic cardiomyopathy

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Brockenbrough-Braunwald-Morrow Sign[edit]

At some point should mention the Brockenbrough-Braunwald-Morrow Sign, which is a decrease in the pulse pressure after a premature ventricular contraction. While the left ventricular pressure increases in the beat after the premature contraction, the dynamic obstruction increases to a greater degree, so that the arterial pressure paradoxically decreases. An individual with a fixed obstruction (for instance, due to aortic stenosis), the degree of obstruction will not change, and the left ventricular and systemic systolic pressures will both increase in the beat after the premature ventricular complex. Ksheka 02:59, Aug 25, 2004 (UTC)


Done. Ksheka 14:09, Sep 26, 2004 (UTC)


This is something to watch: soy diet worsened HCM risks in mice.[1]. JFW | T@lk 00:04, 5 January 2006 (UTC)

Sigwart reference[edit]

Where did Ulrich Sigwart report his first case series with septal ablation? JFW | T@lk 22:22, 1 February 2006 (UTC)


At regular times a professional bodybuilder dies. Afterwards in the autopsy doctors often find a hypertrophied heart. Is there any connection between steroid usage and HC? Sijo Ripa 19:08, 23 July 2006 (UTC)

Answer: That relation I don't know. But I do know that when you workout only one region of your body, for example arms, the rest of your body isn't working. The brain interprets the exercise as a whole body function (we didn't need to be bodybuilders in the savanna) so it makes the heart pump faster and stronger. Because only the arms are at stress his artery's are "opened" to receive more blood, but the rest of the body isn't! It creates a lot of pressure to the heart to pump against almost close vessels, the heart compensates it by growing in size by multiplying the number of cardiac cells and the number of muscle fibers within each cell. This is Hypertrophic cardiomyopathy.

Should there not be an etymology for medical terms? At least people are made aware of the origin of the medical terms and what they mean. For example Hypertrophic from the Greek hyper + trophy and cardiomyopathy from the Greek kardia + mus + pathy..... (talk) —Preceding undated comment added 07:26, 13 September 2013 (UTC)

Diagnostic testing[edit]

Information is needed on echocardiography, Cardiac MRI and ECG in regards to diagnostic testing.

Alcohol septal ablation[edit]

Actually the septal that is infused with alcohol may not be the first septal perforator. What is done in experienced centers is an echocardiogram (I'm not sure if it is a TTE or TEE) at the time of the angiogram. The septal artery is occluded with a balloon and echo contrast (or agitated saline?) is injected distally into the septal perforator. The wall motion is then observed via echo to see if the gradient improves and also to see what portion of the septum will be affected by the ablation. Will have to find a reference or two to add this to the article. Ksheka 14:13, 30 November 2006 (UTC)


Broadening the indication for ICDs: JAMA JFW | T@lk 23:23, 24 July 2007 (UTC)

Heart Attack[edit]

I had Ripley's Believe it or Not on it they showed a woman with this who's symptoms were cured or severely reduced by a forced heart attack. I believe this should be mentioned in the article, though I'm not sure if it has become a possible solution for most, or if this is the only case.

That's what alcohol septal ablation is. Ksheka 12:59, 26 July 2007 (UTC)
I fixed the section of alcohol septal ablation to mention it. I wrote there When performed properly for a reason - The procedure had low success rates at first due to a number of problems, but the technique is now better documented. Ksheka 13:07, 26 July 2007 (UTC)


I had First Respone at my house because a friend was freakinjg out and thought he had it. There computers andthe person that came over said it doesnt exist???

venturi hypothesis of SAM[edit]

The origin of the hypothesis, that systolic anterior motion of the anterior leaflet of the mitral valve is caused by a venturi effect, appears to be Wigle E. D., Adelman A. G., Silver M. D.: Pathophysiological considerations in muscular subaortic stenosis. In Wolstenholme G. E. W, O'Connor M., editors: Hypertrophic obstructive cardiomyopathy. London, 1971, Ciba Foundation Study Group, No. 47, Churchill, p. 63.

Evidence of this that is available on-line ( as of 1/18/10 is the following editorial in Circulation. E. D. Wigle, Hypertrophic cardiomyopathy: a 1987 viewpoint. Circulation (1987) 75: 311-322. There, Dr. Wigle claims the hypothesis on page 312, and the above reference is citation 11.

A contributor having access to the original article might choose to include it as the missing reference in this Wikipedia article.Nhy67ygv (talk) 06:50, 19 January 2010 (UTC)

Merging with article on Hypertrophic Cardiomyopathy Screening[edit]

This merger makes a lot of sense since the article on Hypertrophic Cardiomyopathy Screening is an orphan page, is not too long, and is relevant to people looking up Hypertrophic Cardiomyopathy. Screening is more of a section than a standalone article. Gccwang (talk) 07:15, 19 January 2010 (UTC)

Thank you for raising this; I didn't even realize that the article Hypertrophic Cardiomyopathy Screening existed until your post. Your proposal makes sense. However, the main HCM article is already fairly long and covers a number of topics. I wonder if it might not be desirable to maintain Hypertrophic Cardiomyopathy Screening as a subsidiary page of Hypertrophic cardiomyopathy, with a brief summary paragraph at the main article and connecting links. I suggest this, in part, because the subject of screening is not only a medical one but also a public health (and sports policy) issue that is currently receiving increased attention in the general media (for example a long segment on ESPN's Outside the Lines earlier this week). So the screening article has some potential to grow.--Arxiloxos (talk) 16:08, 19 January 2010 (UTC)
Agree with Arxiloxos – in accordance with Wikipedia:Summary style, we should have a brief summary section, with details at a separate article (“HCM Screening” is currently 11k, which would be too long in the main article).
Accordingly, I’ve written a summary section, linking to the details article.
Gccwang, does this seem good to you?
—Nils von Barth (nbarth) (talk) 00:52, 6 February 2010 (UTC)
Sounds good. Removing merge tags. Gccwang (talk) 00:39, 15 February 2010 (UTC)

abnormal blood pressure after exercise[edit]

From treatment section:"A high risk of suffering sudden cardiac death may be indicated by a ventricular wall thickness greater than 30mm, unexplained syncope, family history of sudden cardiac death, abnormal blood pressures after exercise.."

What is a normal blood pressure after exercise. Does one's BP normally go up or does it normally go down after exercis? (talk) 21:19, 18 June 2012 (UTC)