Talk:Lantibiotics

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A detailed article from Molecular biology on all the Bacillus subtilis antibiotics at http://www.blackwell-synergy.com/doi/abs/10.1111/j.1365-2958.2005.04587.x Rod57 (talk) 16:25, 1 September 2008 (UTC)


Clarification[edit]

I think that "These attributes of lantibiotics have led to more detailed research into their structures ..." might be more accurately phrased as, "Interest in these attributes of lantibiotics have encouraged more detailed research into their structures ...". It's not the attributes that have led to the research. It is people's response to these attributes. I am reluctant to make this edit because it may change the author's meaning. Hughdbrown (talk) 23:53, 1 January 2008 (UTC)


Error in introduction It states that Lantibiotics are antibiotics when in fact they are not. They are different from antibiotics in that they constructed ribosomally while antibiotics are constructed by enzymes. Also Lantibiotics, such as Nisin, are allowed as food additives, this is forbidden for antibiotics. Rhob7 (talk) 18:48, 13 April 2009 (UTC)

I removed the line "In spite of this naming, Lantibiotics are not classed as antibiotics.One reason for this is that they are constructed ribosomally while antibiotics are constructed by enzyme action." because it's just not true. Lantibiotics are classed as antibiotics and are produced by enzymes (LanB, LanC, LanM and so on). Antibacterial activity is the characteristic that makes a molecule an antibiotic, not how they're made. This applies whether it's natural or synthetic. Lantibiotics have antibacterial activity (by definition), and so they're antibiotics. Andy18741 12:00, 1 September 2009 (CET) —Preceding unsigned comment added by 139.18.6.249 (talk)

Bisin[edit]

Hi, I don't know much about chemistry/biology, but I read the news about Bisin, looked it up in WP and then arrived to this page via wikilink. The article says that lantibiotics works against Gram positive bacteria, but if I understand correctly, Bisin changes this. Or maybe the Bisin article is wrong and it really isn't a lantibiotic? (tho 2nd reference[1] refers to it as a lantibiotic). --Langus (talk) 22:34, 20 August 2011 (UTC)

Constituent amino acids[edit]

2-aminoisobutyric acid is not unsaturated (except for the carboxyl which all amino acids have). This should probably be 2-amino-2-butenoic acid (referred to as dehydrobutyrine as I recall) instead. 69.72.27.119 (talk) 05:21, 10 January 2012 (UTC)

incoherent[edit]

"B lantibiotics inhibit peptidoglycan biosynthesis.[2] for discussion of mechanism of action. " FoCuSandLeArN (talk) 19:38, 4 January 2013 (UTC)