Talk:Latent autoimmune diabetes

Improvement of article

This article was in dire need of clarification on the differences and similarites between type 1, type 2, and latent autoimmune diabetes (LADA). I added substantial material including diagnostic testing to help differentiate between the three forms of diabetes and references. Later, when I have time I will also hyperlink diabetes terms to Wiki's definitions.

Hopefully, what is now present in this majorly revamped article, will serve as a solid backbone for others to continue to improve upon (if needed.

I really hope to see this article stay because millions of adults are misdiagnosed as having type 2 diabetes but have LADA and end up insulin dependent for life. It would help many adults to know that not all type 2 diagnosis are correct. Islets of Hope 06:53, 22 May 2006 (UTC)

It is truly important to bring to light the prevalence of adult-onset Type 1 diabetes (LADA or Type 1.5) and the need for correct diagnosis and treatement. In a recent survey conducted by Australia’s Type 1 Diabetes Network, one third of all Australians with type 1 diabetes reported being initially misdiagnosed as having the more common type 2 diabetes. Type 1 diabetes and Type 2 diabetes are different diseases with different genetics, causes, treatments, and cures. Diagnosing an adult with Type 2 diabetes when the person actually has Type 1 diabetes is misdiagnosis and could be construed as malpractice since tests are available to differentiate between the two diseases (antibody testing and c-peptide testing). Misdiagnosis often leads to undertreatment, which hastens the onset of complications and causes needless suffering and potentially death. If the medical community were made more aware that the vast majority of new cases of Type 1 diabetes are adults, then more appropriate care might be given. The appropriate treatment for Type 1 diabetes is exogenous insulin, with intensive treatment begun as early as safely possible after Type 1 diabetes is diagnosed. People who have immune-mediated diabetes, including LADA, should not be treated as if they have Type 2 diabetes. Although Islets of Hope has made a good start, there is some information here that should be updated. First, the United States National Institutes of Health defines LADA as "a condition in which Type 1 diabetes develops in adults." According to the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus (as published in Diabetes Care, Volume 30, January 2007), "Although the specific etiologies of [Type 2] diabetes are not known, autoimmune destruction of beta-cells does not occur." Furthermore, the Expert Committee’s definition of Type 1 diabetes by the clearly encompasses all autoimmune diabetes, regardless of age, which includes LADA (“Type 1 diabetes results from a cellular-mediated autoimmune destruction of the beta-cells of the pancreas. In Type 1 diabetes, the rate of beta-cell destruction is quite variable, being rapid in some individuals (mainly infants and children) and slow in others (mainly adults).”) Redyoga (talk) 23:22, 6 October 2009 (UTC)

Stub classification

I have classified this article as a stub as it needs a lot of work such as wikification and sourcing. Capitalistroadster 06:13, 12 July 2007 (UTC)

Steps for improvement

1. Properly cite references (see wp:cite)
2. Add a table comparing Type 1, 2 1.5 and LADA

Userbox

I'm sorry that I'm not in a position to work on this article at the moment. But I can contribute a userbox... Arikk (talk) 21:22, 26 October 2009 (UTC)

	This user lives with Latent Autoimmune Diabetes in Adults (LADA)

ISU Student Class regarding LADA

Thank you guys on your own improving on this piece of diabetes article in Wikipedia. We students began studying Latent Autoimmune Diabetes three years ago, although at that time not enough information existed which could be really trusted. Some diabetes groups—in particular, the American Diabetes Association—often get LADA confused alongside adult type 01 diabetes too frequently.

Moreover, contrary to whatever certain source on diabetes might be saying, some people with Latent Autoimmune do carry family histories of T2DM in their brothers, sisters, uncles, aunts, parents, nieces, nephews, etc. That's because a TCF7L2 gene has association with type 2 diabetes which is shared with the LADA.

Also, not every Latent Autoimmune Diabetic Adult is skinny or slim—certain Latent Autoimmune resources say that some people affected with the Latent Autoimmune Diabetes are plus sized; these plus sized people often receive incorrect diagnoses and treatment because of their weight and because that TC7FL2 (and possibly certain other genes connected with type two may trigger enough resistance to insulin, making the individual acutally look like classic T2. ISU Students from 129.255.1.116 (talk) 16:48, 23 November 2009 (UTC)