Talk:Myostatin

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This article was the subject of a Wiki Education Foundation-supported course assignment, between 10 January 2022 and 27 April 2022. Further details are available on the course page. Student editor(s): Rajr2020 (article contribs).

Interesting trivia[edit]

  • On the tv-series The Incredible Hulk episode "Death in the Family" (Season 1, ep 2), the protagonist meets an heiress who is being given intravenous injections of a drug called 'Myostatin'. Ultimately, a plot is revealed-- the drug it is revealed that the drug is not ACTUALLY myostatin, but is a poison intended to kill the woman.
    Obviously, this episode aired some 20 years before the discovery of the actual Myostatin.
    Worth mentioning in the article? I doubt it, but.. it is interesting.
    --Alecmconroy 14:26, 17 August 2006 (UTC)[reply]
  • Actually, I think it is worth mentioning. The problem however, is how it should be mentioned. Considering what Myostatin deals with, it seems likely that whoever coined the phrase borrowed it from The Incredible Hulk. That being said, you shouldn't just throw that out there as fact. Citations need to be found. In the same vein, Myostatin is also mentioned in the 2008 Incredible Hulk movie (which is what brought me here in the first place, actually).
  • In the Hulk episode, what is the supposed effect of the fictional drug myostatin? Anthony Appleyard (talk) 11:19, 3 November 2008 (UTC)[reply]
  • As is the case with most stories of that time that were not medical dramas, the details were kept to a minimum. It did not have anything to do with muscle growth, though. I suspect someone on the team who discovered Myostatin borrowed the name from The Incredible Hulk because of the relation between heavy muscle growth and the Hulk rather than the supposed effects the fictional version had in the story.Wyldstaar (talk) 22:16, 19 March 2011 (UTC)[reply]

Citation Request[edit]

Added a citation request to the claim of John Hopkins holding the patent on Myostatin, as a patent being granted to a naturally occuring protein sounds problematic.

There are myostatin patents, like this one which John Hopkins holds. Probably could be worded better. - Z

Double muscled Whippet[edit]

http://farm2.static.flickr.com/1341/727663041_63325260bf.jpg?v=0

A more impressive picture. Probably copyrighted, though. 212.108.17.165 10:18, 6 July 2007 (UTC)[reply]

Article on that whippet (Wendy), available here: http://www.dailymail.co.uk/pages/live/articles/news/news.html?in_article_id=467985&in_page_id=1770. The characteristic overbite of the homozygous mutant is apparent in another picture from the article. —Preceding unsigned comment added by Emw2012 (talk • contribs) 21:07, 11 December 2007 (UTC)[reply]

This article says bully whippets are poorer runners, but elsewhere it's said they're better from the extra muscle. Maybe it varies? —Preceding unsigned comment added by 173.11.36.165 (talk) 14:06, 25 March 2010 (UTC)[reply]


Well, since the studies showed in otherwise healthy mice, they weren't any stronger, significantly extra muscle without extra strength would just make them slower. The section mentions the heterozygous carriers were over-represented and may have made better runners but the overall effects were mild, but the homozygous one, who developed the "double muscles", were poor runner. Since the heterozygous difference are subtle, they do not clearly display the mutation, and similiarly do not develop the problem of too much muscle that the homozygous ones do.

Why is this still locked?[edit]

For that matter, why was it ever locked? No expiration it either. —Preceding unsigned comment added by 99.164.58.127 (talk) 22:30, 18 January 2009 (UTC)[reply]

Future use[edit]

I have a great article about it in russian medical journal - the photo i take from it (http://trener-on-line.ru/index.php?Itemid=34&id=21&option=com_content&task=view). We must point in article where this discovery will be used - by the medical journal - it will be used in the conditions accompanied by risk of loss muscular weight, such, as: 

The long periods of absence of normal physical activity (a long confinement to bed, stay in weightlessness),
The traumas leading long immobilization of groups of muscles,
Oncological diseases,
A number of complications of chemotherapy,
A sepsis, some sharp and chronic infections, including AIDS,
Senile sarcopenia (loss of muscular weight), beginning actually after 40 years.

Westsomething (talk) 09:12, 25 October 2009 (UTC)[reply]

Dead link[edit]

http://listas.cev.org.br/pipermail/cevgenetica/2004-June/000060.html (currently reference 10) is dead. And yeah...why is this still locked? 207.67.17.45 (talk) 20:20, 6 May 2009 (UTC)[reply]

Significant Revision[edit]

I revised this article. There was a lot of misinformation and uncited material. Also there was a paragraph which read as though it was written by a non-English speaker who has only recently started to grapple with the intricacies of the language. Finally there was an amazing amount of detail of myostatin in fish, which is hardly of general interest. All of this material was removed. Gacggt (talk) 02:16, 23 November 2009 (UTC)[reply]

"Blockers" section?[edit]

In some older versions of the article, there was mention about the fact that no true myostating blocker has ever been developed, and pretty much pointing out that all of these myostating blockers one sees announced in sports and bodybuilding websites are fake. I don't see the reference anymore. Does anyone know when or why it has been removed? — Preceding unsigned comment added by Jdsouza (talk • contribs) 21:42, 17 January 2012 (UTC)[reply]

Just saw that the section was removed a couple of weeks ago by some IP address with no other wikipedia editing history. So I just undid their changes. Jdsouza (talk) 21:57, 17 January 2012 (UTC)[reply]

External links modified[edit]

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Proposed merge of Double-muscled cattle into Myostatin[edit]

The following discussion is closed. Please do not modify it. Subsequent comments should be made in a new section. A summary of the conclusions reached follows.
The result of this discussion was…no merge .

Much of the article is about myostatin and not cattle; much of the rest of it is dubious or plain wrong. Justlettersandnumbers (talk) 12:29, 26 June 2022 (UTC)[reply]

Oppose the merge; material that is wrong and unreferenced can be deleted; if it is misplaced, delete or copy it. The topic of Double-muscled cattle warrants separate coverage even if the current page has quality issues. Klbrain (talk) 05:13, 7 November 2022 (UTC)[reply]
corect 2001:8F8:1735:81F1:DCF3:E215:B9FA:5F2 (talk) 05:53, 27 January 2023 (UTC)[reply]
Oppose. Quality should not be a factor in determining splits & mergers. THe topics are related, but distinct. Libcub (talk) 02:39, 19 January 2023 (UTC)[reply]
The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

Joyous! | Talk 22:27, 18 February 2023 (UTC)[reply]

stop removing the picture[edit]

Stop removing the picture of a human with myostatin deficiency. The individual in question has gone through a few genetic tests to prove such deficiency exists in his/her body yet I'm being asked to provide evidence? Is this not a breach of medical confidentiality? Idodabs2 (talk) 11:16, 6 March 2024 (UTC)[reply]

Then please supply documentation for genetic tests supporting myostatin deficiency. Concerning File:Humanmyostatin.jpg, using a medical photograph of a person without their permission is unethical. In addition, there are many alternative explanations including steroid use and/or weight training that could explain the appearance of this individual. The photograph appears more consistent with anabolic steroid use or weight training than a myostatin deficiency. Boghog (talk) 18:58, 6 March 2024 (UTC)[reply]
Listen bog. I've never touched a steroid in my life. Oh, did I mention, that person in the picture is me? Why on God's green earth would I provide you with my personal and individually identifying medical documents, just to appease you and let you allow me to post a picture. Get real. Do you want me to pee in a cup for anabolics too? Idodabs2 (talk) 09:53, 7 March 2024 (UTC)[reply]
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