Talk:Phenyltoloxamine

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Parasympathetic Response[edit]

It is an inhibitor of the parasympathetic response, surely? Not Sympathetic? The benzyl group C2' on the benzene confers anticholinergic activity on h1 antihistamines.

When was this drug withdrawn from the US market[edit]

i remember see a pill that had acethamiophen and phenyltoloxamine in the 1990s but i haven't seen it in a few years so i want to know when it was withdrawn from the US market — Preceding unsigned comment added by A8v (talkcontribs) 12:17, 15 February 2015 (UTC)[reply]

Phenyltoloxamine was designated as as category II OTC agent- was not found to be efficacious for use in OTC Cough Cold Drug products CFR 310.545. It was being re-evaluated as an adjunct in analgesics in 2011.. Available at: http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/cfrsearch.cfm?fr=310.545 unsigned

Phenyltoloxamine was removed from OTC pain medication "Percogesic" as of January 2011. The new formulation contains diphenhydramine with acetaminophen.unsigned

Phenyltoloxamine was used in a number of unapproved prescription medications, in combination with acetaminophen (e.g, ACUFLEX, BEFLEX, ZGESIC). The FDA started reviewing unapproved prescription drug products and, as of 2014, most of these products are no longer marketed. unsigned

There is currently a shortage of phenyltoloxamine.unsigned — Preceding unsigned comment added by 128.197.222.198 (talk) 22:40, 4 March 2015 (UTC)[reply]