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Fast/Slow Block[edit]

I'm not well acquainted with the topic, but I believe reference to the fast block and slow block and egg takes to prevent polyspermy is necessary. --Brazucs (TALK | CONTRIBS) 00:32, 19 April 2006 (UTC)

The chapter "mythology"[edit]

This chapter was wrongfully removed yesterday. I responded to the editor who removed it, but they didn't respond, so I am reverting to the last stable version. Any user who disputes, may discuss this here.

Really, the source that was wrongfully removed, doesn't mention the term "cell" - but rather the term: "sperm/semen" only, however, this source does discuss poly-spermy (poly + spermy, i.e. "multy-sperm"), and it even states clearly that a woman can get pregnant by sperm/semen of several men - all at once - on some rare biological conditions (indicated ibid.), and it also states that those conditions enabled Goliath to have one hundred fathers.

Eliko (talk) 08:51, 15 March 2011 (UTC)

It's undue weight. DS (talk) 17:15, 17 March 2011 (UTC)
Agree with DS. It's undue weight and irrelevant to the article. However, you might want to contact the Foundation as this article is clearly the Wrong Version. Basket of Puppies 21:14, 17 March 2011 (UTC)
The chapter you removed is not the wrong version, because it has nothing to do with edit-war, because edit-war means: reverting to a previous version - without considering the claims of others against that previous version, while the chapter you wrongfully removed - was improved again and again by me - according to your comments about "irrelevance" - without reverting to a previous version. Further, The chapter is supported by User:(MOB)DeadMeat, and is also supported by User:Chrishatch1973, and is also supported by User:Eliko; whereas the removal of the chapter is supported by User:Basket of Puppies and is also supported by User:DragonflySixtyseven only; So which option is more consensual? Returning the chapter, or removing it? Eliko (talk) 11:01, 18 March 2011 (UTC)
I am not able to find any sources on the topic of polyspermy that discuss this particular factoid. Without such sources, inclusion of this section is grossly undue weight, and it should be removed. The information is included at Goliath, though the sourcing there is also insufficient. The section here is polemical, effectively unsourced (the single primary source does not support the main thrust of the paragraph), contains an unsourced direct quote (it looks like a translation from the Jerusalem Talmud?), and would be only weakly on topic even if a source could be located. Eliko, the links you present above do not appear to support your contention of a prior consensus; please consider also that consensus can change. - 2/0 (cont.) 18:45, 18 March 2011 (UTC)

I am considering developing this page further as part of an educational assignment in Fall of 2013. If someone else is also working on this, please send me a message and let me know soon, so we donʼt duplicate initial efforts in page development. Kohw 10:01, 6 October 2013 (UTC) — Preceding unsigned comment added by Kohw (talkcontribs)

Possible suggestion to the article[edit]

This article is excellent in general background information and processes involved with polyspermy. However, this article would be better for people to understand the concepts behind polyspermy with less confusion if more details are added to it. For example, pictures, or visual of the steps, regarding the process behind polyspermy, fast, and slow block will provide people with more clear explanations. In addition, additional helpful information can be brought from information provided in NCBI bookshelf (on the text Developmental Biology, 6th edition). The full citation for the information is: Gilbert SF. Developmental Biology. 6th edition. Sunderland (MA): Sinauer Associates; 2000. Gamete Fusion and the Prevention of Polyspermy. Available from: The information provided by this site gives us better insights on normal gamete fusion. Once this information is provided, information from other web or text can be used to explain what causes inviable zygote in polyspermy. Further, this site provides detailed information on prevention of polyspermy, starting with comparison between monospermy and polyspermy then providing details of fast and slow block. This article provides information of fast and slow block but is not detailed. This site gives details on how sodium and potassium concentration and change in resting membrane potential plays a role in fast block. It also gives details on cortical granule reaction (process of reaction and how calcium affects this reaction) and zona reaction in slow block affects preventing polyspermy. Furthermore, the article can be improved by using information from research article from PubMed that is provided in the NCBI site. The full citation is: van der Ven HH, Al-Hasani S, Diedrich K, Hamerich U, Lehmann F, Krebs D. Polyspermy in in vitro fertilization of human oocytes: frequency and possible causes. Ann N Y Acad Sci. 1985;442:88-95. PubMed PMID: 3860066. It provides information on the research done on polyspermy in in vitro fertilization of human oocytes (frequency and possible causes of polyspermy as well as possible methods to reduce polyspermy). Such research reference could give readers a better understanding on this topic. Other than some potential details that could be added, this article was clear on information provided! Kohw 02:45, 7 October 2013 (UTC) — Preceding unsigned comment added by Kohw (talkcontribs)

What happens when polyspermy results in a viable zygote?[edit]

In the introduction section, it reads "Usually, the result (of polyspermy)is an inviable zygote." Please expand on this. Can polyspermic zygotes become living babies? If so, What is the average life span for polyspermic babies? Curtis Bixenstine (talk) 03:36, 4 February 2014 (UTC)