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Before I began editing, these pages were a jumbled mess of confused science and faux-science that had clearly been compiled by recreational marijuana users with minimal understand of how solid research is conducted or reported. Most of the sections were written independently and did not read cohesively when considered by page; as such much of my efforts were spent cleaning up the inconsistencies, miscitations, and straight up fallacies that littered each topic discussed. In addition, I added more citations from appropriate and current research and reorganized the pages so that they are presented in a more digestable format. In summary, these pages on endocannabinoid receptors were not lacking attention before my edits, but had rather received too much attention from people who just did not know what they were talking about. I have simplified, clarified, and expounded where appropriate with the intention of creating a more cohesive and through product. The extent of these edits are subtle, but were based on eight research pages that I read dealing with the topics I addressed Wyliea (talk) 01:52, 7 December 2011 (UTC)
Since this is a "talk" page
I'm "in medicine" and just can't get on the bus with the marijuana people. I mean, weed may have it's benefits (so does heroin) but as you've stated above, the recreational users have bastardized the literature with anecdotal testimonial "facts."
My big one is that if indeed this is a credible treatment, would you give your 10 year old cancer patient/child of your own a refer and teach him how to "fire up?" "No Johnny. You've got to inhale it deeply and hold it into your lungs. Watch how daddy does it..." Blondesareeasy (talk)Thanks for playing. —Preceding undated comment added 22:36, 1 February 2012 (UTC).
Your argument is based on the logical fallacy "Reduction to Absurdity." By your logic, Johnny wouldn't get the 'birds-n-bees lecture'; he would watch live demonstrations of safe-sex and then perform supervised demonstrations to prove the lesson was learned.
This article is about Delta-9 Tetrahydrocannabinol, which is only one of the cannibinoids extracted or synthetically produced to provide an effective treatment for cancer patients. Based on the article, nabilone (marketed as Cesamet in the USA) would be the preferred method of treatment and is a fast-acting mouth spray. It seems unlikely any doctor would prescribe lung-damaging treatments if a safer, equally-effective and less hazardous alternative were available. Though it does seem strange that 10-12% of children in school get dosed with amphetamines to 'cure' them of their intolerance to sitting in a chair seven hours a day like 'normal' children know to do.
You want to talk about anecdotal evidence? How about the 'studies' relating violent crime to illegal substances? If they weren't illegal there'd be no need to visit criminals. That's basically the definition of statistical entrapment. There will always be higher incidence of violence in black-markets. The police and politicians know this, but the conclusions of the studies provide misdirection away from 100%-correlated causal factor.
My only concern in this matter is the perversion of logic, reasoning and argumentation. Ritual suicide by alcohol and tobacco: OK, cannabis: NO WAY. Manufactured in China: OK, cigar from Cuba: NO WAY. These are trivial examples.
I find it quite ironic that, in the United States, marijuana is a schedule 1 substance meaning, among other things, that it has no medical benefits. However, marinol is marketed as a medical evaluation of marijuana to assist in medical conditions and actually has a medical value, and is hence a schedule 3 substance. Why is it that if the primary substance has no medicinal value at all, but a product which is basically just THC, the assumed primary ingredient in marijuana (the primary substance), does have medical value. Where's the logic in that? Styk0n (talk) 08:30, 12 November 2012 (UTC)
"Talk page" refers to conversation about the article itself and how to improve it, not debate about the subject of the article. If you feel the article as it stands misrepresents THC, gather your sources and make edits. 22.214.171.124 (talk) 16:38, 21 May 2013 (UTC)
Boiling point of THC
The old wikipedia page got the number 157C somehow. Looking this up doesn't seem to find any real sources. So I've removed that number and placed a number given to me by the Royal Society of Chemistry from their analytic database. This other page also uses this number so I figure that should be a good start. http://en.wikipedia.org/wiki/Cannabis_(drug) LegacyWeapon (talk) 18:07, 11 March 2012 (UTC)
- I looked at the ChemSpider source you cited, and I cannot find the value you reported (199.14 °C at unspecified pressure so assuming 1 atm) anywhere on it. For example, looking in the Properties section, I don't see a boiling-point in the "experimental" tab. In the various "predicted" tabs, I do see:
- "390.448 °C at 760 mmHg" for ACD/Labs
- "407.23" and "200 @ 0.02 mm Hg deg C" EPISuite
- Those are all pretty far off of 199 °C at 1 atm. Conversely, the previous 157 °C value at 1 atm is exactly what ref it had listed says. That ref has a data table that notes "values obtained from various sources, primarily Buckingham, 1992; Guenther, 1948; Parry, 1918; and Mechoulam (personal communication, April 2001)." Because I was unable to verify your value, I reverted back to the previous. Would be useful to find the underlying source for the 157 value, expecially since it is so different from the predicted results. But predicted values are only of limited reliability, especially since not reported in an actual peer-reviewed source, so I think we're stuck with either 157 or maybe nothing (per lack of close agreement among sources). DMacks (talk) 18:31, 11 March 2012 (UTC)
- That other page states "the boiling point of THC is 390.4 °F (199.1 °C) at 760 mmHg pressure", cited to the chemspider source. Notice the 390.4 value...perhaps the editor who wrote the wikipedia content just misread the units when reporting it? I'm tagging that value there as a point of concern. DMacks (talk) 18:43, 11 March 2012 (UTC)
Shouldn't its legal status be updated to include 2012 election changes of medical and recreation cannabis, or not because cannabis s. is not thc. — Preceding unsigned comment added by 126.96.36.199 (talk) 01:46, 6 January 2013 (UTC)
- I don't think that makes the difference. Even if it's only "cannabis" that is now legal and not "THC", it would still be relevant to this article. So go ahead and add it in there. Charles35 (talk) 02:46, 6 January 2013 (UTC)
Vaporization point (and boiling point)
IUPAC NAME IS INCORRECT
Gentlemen I would like to bring to your attention that the stereochemical identities for the IUPAC name for THC are incorrect. The two chiral centers should have "R" as their stereochemical identity not "S". Solving the chirality for the two chiral centers in the structure also shows "R" not "S". This needs to be fixed right away. This is Dr. Mark A Olson of Texas A&M University Corpus Christi, assistant professor of chemistry. I was alerted by my students to this error and verified it. Please see that it is corrected. — Preceding unsigned comment added by 188.8.131.52 (talk) 00:36, 24 April 2013 (UTC)