From Wikipedia, the free encyclopedia
Jump to: navigation, search
WikiProject Pharmacology (Rated B-class, High-importance)
WikiProject icon This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.
B-Class article B  This article has been rated as B-Class on the project's quality scale.
 High  This article has been rated as High-importance on the project's importance scale.

Tramadol as a SNRI in the first place[edit]

The effect of tramadol is mostly due to its ability to inhibit the reuptake of norepinefrine and serotonin. In addition one of its isomers is a serotonin releasing agent. The effect on the opioid receptors is just a minor effect. Hence the first statement should be that tramadol is a SNRI and serotonin releasing substance with additional minor opioid agonistic effect. — Preceding unsigned comment added by an unknown user 10:49, 21 September 2013 (UTC)

Recreational use[edit]

Removed the following comment. It was uncited and reads like a suggestion to abuse tramadol (if someone is gonna abuse a drug then tramadol is probably not the one to abuse) and I also don't like the idea that someone might follow this advice and risk endangering someone, depending on their job, or risk failing their drug test. If someone can find a citation I'd be more inclined for this to stay but even then only if this is a notable phenomenon (by this I mean people abusing tramadol in preference to other drugs *specifically* in order to be able to pass a drug test). Without some decent evidence I think we can assume this is apocryphal.

"Using tramadol as recreational drug may also be preferred because it is one of the only opioids that is often not screened for by standard urine drug-tests." Edit: If anyone wants this kind of information there are plenty of forums dedicated to it. Privateiron (talk) 01:47, 22 August 2012 (UTC)

Controlled Status[edit]

Tramadol is not currently a Controlled Substance in WV or Mo . (talk) 13:38, 1 May 2013 (UTC)

Atypical Opioids[edit]

Tramadol is an atypical opioid (reference). I feel that this deserves a mention in the first paragraph, i.e.; "Tramadol ... is a centrally acting, atypical opioid analgesic used to treat moderate to moderately severe pain." Thoughts?

(Psychonaut25 - 13375p34k / C0n7r1b5 04:43 AM EST, 15 October 2013 (UTC))