Talk:Vitiligo

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Traditional Chinese Herbal Medicine?[edit]

Can someone please remove or clean it up? The grammar is poor and there are no citations listed to support it's validity. —Preceding unsigned comment added by 98.108.135.208 (talk) 22:27, 17 November 2010 (UTC)

Andy Warhol?[edit]

Did Andy Warhol have this condition?

transplants of melanocytes to cure vitiligo[edit]

Hi success with transplantation of melanocytes something new in 2004??? This was possible already 1987 please check the litterature: 1: J Invest Dermatol. 1987 Sep;89(3):219-24.

% of people wit Vitiligo[edit]

The article is contradictory. It says "The populattion incidence is thought to be 1-2%" Then it goes on to say "It is a very rare disease/rare condition affecting 1 in 2000 people". The two statements dont add up. Generally, what I have seen is ~1% of the population has it. But I dont know of any reliable data to back that up.

Is it a disease?[edit]

Yes[edit]

Please see the definition of disease in a dictionary:

Dictionary.com - http://dictionary.reference.com/browse/disease disease- a disordered or incorrectly functioning organ, part, structure, or system of the body resulting from the effect of genetic or developmental errors, infection, poisons, nutritional deficiency or imbalance, toxicity, or unfavorable environmental factors; illness; sickness; ailment.

Merriam-Webster - http://www.merriam-webster.com/dictionary/disease disease - a condition of the living animal or plant body or of one of its parts that impairs normal functioning and is typically manifested by distinguishing signs and symptoms : SICKNESS, MALADY

Also see,

- http://www.niams.nih.gov/hi/topics/vitiligo/vitiligo.htm
- http://www.aad.org/public/Publications/pamphlets/Vitiligo.htm


Is vitilgo an hereditary disease?

"It is hereditary in one third of those affected" [1]

Vitiligo may also be hereditary, that is, it can run in families. Children whose parents have the disorder are more likely to develop vitiligo. However, most children will not get vitiligo even if a parent has it, and most people with vitiligo do not have a family history of the disorder.[2]

Vitiligo, like Psoriasis, is thought to be hereditary. Even if your immediate parents or grand parents do not have Vitiligo, they may have had another genetic issue that is loosely associated with Vitiligo, such as thyroid problems or diabetes etc.[3]

According to these links it seems it is. Richard Cane 19:05, 1 Mar 2005 (UTC)

I'm a black woman who has lived with vitiligo since age 12 (now over 50) with a sister (8 years younger) who also has vitiligo. In my case, I don't have "significant" gray hair, given that most of my scalp has lost its pigmentation (no gray around temples and neckline; must comb hair to find a single strand here and there at the top of my head; the gray hair is probably due to aging given my age). Passed on by heredity? Dunno, but had once asked my own mother if anyone else in the family has vitiligo besides my sister and me; from what I've been told, an uncle on mother's side had vitiligo. lwalt 07:56, 18 March 2007 (UTC)

I have an identical twin brother and he has never had any sign of vitiligo where as I get spots all over my body. I have contacted the vitaligo society and they are taking further tests. Neither of us have had thyroid or other such problems.

I have vitiligo and am fine with that, like the person under the "no section" but that doesn't make the cause of it any less auto-immune related disorder.

No[edit]

I have vitiligo myself, and I do not consider it a disease but rather a cosmetic issue (in some cultures). Just because some doctors and pharmaceutical companies try to make money off of us does not make our natural skin colouring a problem! Calling our white patches a disease only legitimizes the discriminatory treatment that some people inflict on us. The only problems associated with vitiligo are sensitivity to the sun and social stigma. But no one considers other fair-skinned people, who are also sensitive to the sun, to have a disease; and no one considers dark-skinned people, who often face stigma in racist cultures, to have a disease.

Rosemary Amey 00:11, 8 November 2006 (UTC)

  • RE: Vitiligo is a mild autoimmune disease. I doubt it is the intention of the medical profession to stigmatise sufferers. It has in rare cases been associated with bone-marrow transplants: where a patient receives the immune system of another person. The recipient can be attacked by the donor's immune system; a phenomenon known as graft-versus-host disease. Interestingly, some autoimmune diseases possessed by the donor may also be transferred as the transplanted immune system retains the dysfunctional ability to attack the body's own antigens. Here's a paper on this phenomenon: http://www.nature.com/bmt/journal/v36/n8/full/1705137a.html Fortunately the effects of vitiligo are only cosmetic, unlike other autoimmune diseases such as scleroderma, lupus or rheumatoid arthritis. —Preceding unsigned comment added by 79.71.96.66 (talk) 22:57, 7 July 2009 (UTC)


I don't think it matters whether we as sufferers consider it a disease or not - the article states that it is a skin condition, which should be acceptable to both those who want to maximise and minimise its impact. DavidFarmbrough 08:44, 8 November 2006 (UTC)

It says condition now because I went through and changed all the spots calling it a disesase. :) -- Rosemary Amey 23:18, 17 November 2006 (UTC)

There's lots of good information at [4], all of which is PD-USGov, so we could incorporate it into this article. -- ke4roh 19:00, Mar 14, 2005 (UTC)

I'm pretty sure not calling something what it is doesn't change it. By definition Vitiligo is a disease. Let's be objective. Ijustcan'tthinkofauniqueusername (talk) 19:36, 9 July 2009 (UTC)

Lack of sensation[edit]

I have vitiligo. I note that in the areas of skin affected by the disease, that I have noticebly less sensation than in other areas. Is this just me or do other people have this? If they do, then it is significant to be included, I think. User:DavidFarmbrough 09:00 (BST) 17/5/'05]]


I am curious why the literature on vitiligo keeps identifying it as a skin disease/disorder when melanocytes clearly are derived from the neural crest and are, therefore, an extension of your nervous system. As melanocytes make melanin, they move the molecules along 'dendrites' which are projections of neurons. That should help clarify how you would have less sensation in affected areas of the body.

Someone should add a link between these articles vitiligo, melanocytes, and neural crest. Neser (talk) 08:44, 28 June 2009 (UTC)


BramVdb: About the lack of sensation... I have the same impression! Not that it is really a big difference in sensation, but indeed I feel slightly less in the infected areas.

Some other remarks:

1) Also I sometimes (very rarely, like twice a year) have rashes on the infected skin. These rashes seem to leave some new pigments but they dissapear within a week.

2) I am also having other immunity related deseases like mentioned on the website.

3) The hair growing on the white skin also becomes white

4) Every summer the spots become bigger. I don't think it is just a matter of becomming visible because of skincontrast, I think the tanning actually burns healthy skin and triggers new vitiligo by doing so. That would be simular to the way that vitiligo can be triggered by small wounds. In other words, I believe that irritation (by burning for example) of the skin can be a cause of vitiligo. Maybe that also explains why some cosmetic products are said to be a cause of vitiligo. Maybe those products irritate the skin as well.

5) I have seen that several websites talk about a relation between vitamine B12 and vitiligo.

6) I have read 2 contrary things about the risk of cancer! The first source says that vitiligo infected skin does not longer give enoug protection against the sun and therefore can cause skincancer. The second source says that vitiligo patients lose their melanocytes cells. These are the cells that create pigments. Those cells are also the cause of melanoa-skincancer. In other words, vitiligo protects against skin cancer! Recently they have even started curing skin cancer by trying to envoke vitiligo with those patients! (At least one advantage to the annoying white spots)

—Preceding unsigned comment added by 81.245.121.70 (talkcontribs) 02:31, 20 September 2006
I have a feeling the spreading is coincidence more than anything. I'm in the process of writing a review article on the development of phototherapeutic vitiligo treatments over the past decade, and the evidence for UV radiation initiating repigmentation is overwhelming (though there still seems to be little, short of surgical grafting, which could be considered effective for hands and feet).
First I've heard about vitamin B12, though vitamin D analogues such as calcipotriol have shown some moderate results.
By the way, no one knows for sure what causes vitiligo, so if you hear about skin products or anything else triggering it, take it with a grain of salt. Doesn't mean it's wrong, just means it's speculative at this point. --203.206.183.160 09:08, 2 October 2006 (UTC)

I'm a long time vitiligo sufferer, and I too have noticed that vitiligo definitely spreads every time I am in the sun. 41.241.237.249 06:43, 24 January 2007 (UTC)


I wish this article included a list of famous people who have vitiligo. Besides, Michael Jackson (whom I don't believe) the author of "The Lord Lifted Me Despite the Church" has it.

Also, I know Black and Asian Indians who have vitiligo, but I've never seen other groups have it.

The above was added 22 July 2005 by 143.231.249.141

You won't have noticed it in paler skinned people. DavidFarmbrough 09:51, 25 October 2005 (UTC)
Wasn't there some African-American activist who lost pigmentation in his older age and was harassed by the youths in his neighborhood who took him by a white "intruder"?

Michael Jackson uses -makeup- ?? What's all this talk about bleach then?

Various[edit]

Light-skinned people can certainly have vitiligo. It just may not be very obvious, particularly if those people avoid the sun & always use sun screen.

I suspect that Michael Jackson isn't presently using makeup to even out the effects of vitiligo on his skin tone, but has had his skin depigmented.

Although vitiligo itself maybe harmless, it is associated with other more serious auto-immune diseases people should monitor for (e.g. hypothyroidism, diabetes, rheumatoid arthritis).


My father always had small patchs of vitiligo on his back, which would became even smaller when he was exposed to the sun for long periods of time, but never went away entirely. His brother had a severe case on his hands and elbows. Their mother found out she had it in her 30's, and by the time she was 60 the condition had overtaken her whole body. My brothers (30-40) and I do not have any sign of it, but I've hypothyroidism. My father and his family are caucasion. —Preceding unsigned comment added by 24.36.153.153 (talk) 22:23, 28 August 2008 (UTC)

India[edit]

The article states: "The incidence in other countries such as India is thought to be higher." Isn't this just because it's easily noticed in people with darker skin? DavidFarmbrough 07:37, 7 June 2006 (UTC)


A: While there are no official numbers on this, I see more Indians/S.Asians who have Vitiligo. This is not a case of it being more obvious because of the darker complexion. If that were the case, the above statement should hold true for preople of African descent. Also there is some ongoing debate about how an Indian diet that includes turmeric may influence the development of Vitiligo. Of course, there is the point that there are over 1.5 billion S. Asians and so the probability of finding a S. Asian with Vitiligo is higher.

Causes, chronic and related diseases[edit]

I've read an article (written by a dermatologist, mind you, but in swedish) that said that vitiligo had been connected with several other autoimmunological diseases, for example thyroid failiure, diabetes and pernicious anemia. I'd like a link to a good english article about this before I add it though... The swedish article can be found at [5]

Also, should'nt there be a mention of the causes of it (e.g. that the pigment cells are attacked by the immune system) in the intro? The article does metion Vitiligo is thought to be an auto immune disease. The article could use a "Causes" sub heading that explains the different theories for vitiligo in detail.


And last but not least, is it considered a chronic disease? And if so, should'nt that be mentioned in the intro? Hotdogger 21:14, 29 June 2006 (UTC)

Edited to include the word chronic in the intro.

This article should be cleaned up and made more detailed. Something along the lines of the psoriasis article.

similar skin conditions[edit]

I thought one of my friends had this, but upon looking at the article, vitilgo seems to be only lightened patches of skin. My friend is caucasian and has dark patches on his arms. I was hoping to find a section at the bottom of the article directing me to a similar skin condition... so... is darkened skin patches vitiligo as well, or is it something else? --geekyßroad. meow? 02:02, 21 September 2006 (UTC)

Darker skin patches definitely not vitiligo (assuming you ar ecorrect in your assessment - i.e. is teh darker patch of skin all that remains of teh norml skin colour and everywhere else is teh lighter skin). That said, for darker patches lots of causes (?whole body or discrete patches, static in size or spreading) and wikipedia is not the place for medical advice, perhaps suggest to your friend that they see tehir pown doctor ? (Ring worm and Pityriasis versicolor might be worth checking). David Ruben Talk 02:28, 21 September 2006 (UTC)
Sounds like some kind of hyperpigmentation - pretty much the exact opposite of vitiligo. Then again, maybe he just poured silver nitrate all over himself :D. Nasty stuff, I can tell ya... makes your fingers look gangrenous... --203.206.183.160 09:16, 2 October 2006 (UTC)

question[edit]

can vitiligo change someone's genetic makeup? i just have ot ask cause michael jacons kids are white and dont look half-black at all and it teases my brain thinkin about it.Angelofdeath275 05:55, 1 October 2006 (UTC)

No, it can't. --203.206.183.160 09:16, 2 October 2006 (UTC)

makeup artists — Preceding unsigned comment added by Markeching (talkcontribs) 21:43, 25 October 2011 (UTC)

Psychological effect[edit]

I don't believe that vitiligo is directly responsible for any psychological effects as claimed in the article. These effects seem to be more socialogical - such as stigmas and vanity, which both depend on the perceptions of other people, or how individuals perceive other people's perceptions. I think the mention of stigmas attached to vitiligo is valid, but rather than call this a "psychological effect", I feel it should be called "socialogical impact" or something to that effect.

--Man in shack 00:33, 19 March 2007 (UTC)


I have to agree with your opinion, I am in favor of a change to "sociological impact" instead of "psychological effect". Numerous articles are available on that topic, I'll try to find one and come back to add more to the discussion and/or article.

­Francis The Bird 14:59, 23 May 2007 (UTC)

Psychological Source[edit]

I wanted to tell one of my personal experiences with vitiligo. I have vitiligo for a couple of years now I'm a student following a bridge program to change my bachelor into a master degree. I'm always under stress.

One of the first signs I had of vitiligo was my skin getting white on the inside of my knees. In a second phase I started to have some white eyelashes. At that time I didn't know I had vitiligo. Sometimes the number of white eyelashes increased sometimes it decreased. It seemed to me that I had those white eyelashes because I was under a lot of stress at that time. I think that was a first sign to come to my conclusion.

Last year I had a simular experience. I just had a long period (about 2 months) of examinations and schooltests. And for the first time in 2 months I saw my girlfriend. We went having dinner together and I spend the night with her. The next morning I woke up with a lot of rashes on my skin. It looked very strange. A couple of days later it seemed like I was starting to repigment. This repigmentation however started to go away again bit by bit, allthough on occasions I have new repigmentations on those same spots. It seems to me that the repigmentation was started because I just had a really good time for the first time in months.

Some say vitiligo is related to hormones, which are related to the anti-immune system. So I think it all makes sense in that way, from my point of view. So enjoy relax and have a good time, who knows what can happen :).

Someone in my family has it, and he gets quite distressed with this. —Preceding unsigned comment added by 67.188.195.216 (talk) 06:37, 8 February 2010 (UTC)

Why depigment?[edit]

Wouldn't it be easier and more aesthetic to simply dye yourself all over? I mean, if I was born black and suddenly my color shifted and I had to pick one or the other, I (well, I'd pick patchy, it looks cool) would definitely choose black over white..

It's harder than simply "dyeing yourself" the point is that the melanin can't maintain color anymore. Tatoo's don't work either, they tend to jsut agrivate the area then the vitiligo will spread around the tattoo.

Treatment[edit]

I have minor vitiligo on my hands. My doctor has told me that his understanding of current medical opinion in the UK is that steroid cream actually makes things worse. Seems somewhat at odds with the article which says that the "traditional treatment given by most dermatologists is corticosteroid cream" (even though it cites a paper) - JonRB 12:14, 5 July 2007 (UTC)

Well, take a look at this link. It might interest you, and there was nothing written about it in the main article!!!!!!!!!!
http://www.presstv.com/detail.aspx?id=42557&sectionid=3510210 —Preceding unsigned comment added by 192.167.209.10 (talk) 18:02, 28 February 2008 (UTC)

Just thought I should mention that the "Non-Segmental" paragraph of "Treatment" does not state any kind of treatment.--Hodeken (talk) 09:48, 22 November 2011 (UTC)

Lead picture?[edit]

I'm wondering if we can't get a better lead picture, with the disease more pronouced, such as in this picture: http://i.l.cnn.net/cnn/2007/HEALTH/conditions/12/18/turning.white.ap/art.vitiligo.thomas.ap.jpg --HoneymaneHeghlu meH QaQ jajvam 20:26, 18 December 2007 (UTC)


Vitiligo is curing minimum 6 weeks and maximum is 3 months . If all regulations mentioned here is respected the developing of disease is stopping for 6 weeks and withdrawal of vitiligo depending of that which layer of cells from the skin is destroyed and whole withdrawal is happen 90 days.

The healing is recognizing after 21 day from taking therapy where in the middle of spots (Vitiligo) is creating a pigment which is enlarging periphery. Very often is happening Vitiligo to withdrawal after stopping with therapy and explanations of this is in the time of therapy are ordering all systems and Vitligo withdrawal after longer period.

[6] http://www.alternativnamedicina.com.mk/index.php/en/manuals/manual-for-skin-diseases-vitiligo see more of this article —Preceding unsigned comment added by 95.86.33.179 (talk) 21:38, 3 August 2009 (UTC)

External links[edit]

External links to patient support groups (especially online chat boards), blogs, and fundraising groups normally not accepted on Wikipedia. Please read the external links policy and the specific rules for medical articles before adding more external links. WhatamIdoing (talk) 00:41, 13 January 2008 (UTC)

Eddie Panlilio[edit]

I added this since this priest made history here:

P.T. Barnum[edit]

P.T. Barnum exhibited "Negroes turning white" in his circus. "negroes+turning+white"&source=bl&ots=HB0AMiNwr-&sig=3IRHgevVak9ZIUEZbRu-5O4nrUc&hl=en&ei=PP5DStbYL5OwswPD3bTuDQ&sa=X&oi=book_result&ct=result&resnum=1

Incidence reference[edit]

I'm not quite up on how to create a citation; I looked in this article, and it seems like you are supposed to specify a bunch of information. I found a reference to 0.5% - 1% incidence rate worldwide, on [7], and was going to add it as a reference to the "citation needed" in the opening paragraph, but I didn't have most of the information (e.g. author name, published date, etc.), since I only found it on a web page. Are there articles on how to cite correctly, and how to find the other information needed for a good citation? Prosthetic.Lips (talk) 01:29, 29 June 2009 (UTC)

I found a review article cited which claims 1-2% (Huggins), I believe this is where the figure in the article came from. However, doing a lit search, this seems to be too high. Nath SK et al (pmid 7977362) point out that the 1% estimate for the US is biased high, and other population-based studies (which would be expected to be more accurate) all show a prevalence of less than 1%. I've updated the article with this figure, and cited the source. Oasisbob (talk) 18:58, 9 July 2009 (UTC)

This is "common"?[edit]

A claim like this requires evidence. 99.148.165.99 (talk) 05:57, 5 July 2009 (UTC)

Recent Clinical Treatments[edit]

In January 2009, Researchers at Banaras Hindu University in India announced the results of a study on 50 patients with Luekoderma (Vitiligo) using a poly herbal ointment based primarily on black chick peas also known as Kala Chana. The black chick peas apparently contain elevated levels of an enzyme that is important in repopulating melanocytes. It is important to note that most hummus in the US is made from the white chick peas (thanks go to the Vitiligo Corner on Nathalie Pelletier's website for corresponding with the lead research team to get clarifications from them on the exact pea/bean).

The most striking result came from one of the people in the study who had 100% restoration of pigment in prefiously depigmented patches in 24 days. Apparently he claims to have increased his dietary intake of the Kala Chana peas during the study. The other people in the study showed significant improvment over the 8 month long study.

This is the first time I have posted on Wiki, so please excuse any mistakes I may make. This is important research and needs to be put on the main page, I suspect, by someone who is on the task force. Please find below several links which are useful resources.

Thanks http://vitiligocover.com/chickpeas-for-vitiligo-straight-from-the-scientist/

http://www.thaindian.com/newsportal/india-news/banaras-university-scientists-claim-chickpeas-can-cure-leukoderma_100149172.html

http://satyameva-jayate.org/2008/02/20/black-pepper-vitiligo-cure/

http://74.125.47.132/search?q=cache:Y0dEm88yTXAJ:www.zeenews.com/sci-tech/health-medicine/2009-01-27/502035news.html+BHU+chickpeas+vitiligo&cd=1&hl=en&ct=clnk&gl=us

http://www.newkerala.com/topstory-fullnews-81906.html

http://www.google.com/search?hl=en&q=Kala+Chana&btnG=Google+Search&aq=f&oq=&aqi=

http://www.medindia.net/news/Leukoderma-Cured-With-Chickpeas-Banaras-University-Scientists-46958-1.htm

http://vitiligocover.com/tag/nathalie-pelletier/

http://74.125.47.132/search?q=cache:bkRDJGQEkDkJ:www.geocities.com/ybtimsbhu/+www.geocities.com/ybtimsbhu&cd=1&hl=en&ct=clnk&gl=us —Preceding unsigned comment added by Alexismyboy (talkcontribs) 00:29, 7 July 2009 (UTC) actually this can affect the whole body —Preceding unsigned comment added by The man in the mirror (talkcontribs) 14:23, 8 July 2009 (UTC)

External Links to clinical images[edit]

Would it be worthwhile to add links to sites with clinical images of the condition given we only have one photo available on the page?

http://dermatlas.med.jhmi.edu/derm/result.cfm?Diagnosis=45 http://dermnetnz.org/colour/vitiligo.html http://www.visualdxhealth.com/adult/vitiligo.htm http://dermis.multimedica.de/dermisroot/en/37282/diagnose.htm —Preceding unsigned comment added by 208.3.217.201 (talk) 14:13, 9 July 2009 (UTC)

Pronunciation[edit]

How is "vitiligo" pronounced? My guess would be either ve-ti'-le-goe or vi-te-lee'-goe. Could someone add the IPA pronuciation to the lead sentence? — Loadmaster (talk) 21:40, 16 July 2009 (UTC)

Okay:
Vitiligo (US: /ˌvaɪdlˈaɪgoʊ/, /ˌvɪdlˈaɪgoʊ; -ˈigoʊ/, UK: /ˌvɪtɪˈlʌɪgəʊ/) is a chronic disorder…
If you're American, choose the one you like; sources are all over the place. E.g.: AHD's first syllable is like /vaɪ/ only, while M-W and Random House only pronounce it like /vɪ/. NOAD2 lists both, with /vaɪ/ before /vɪ/. —RVJ (talk) 06:47, 18 July 2009 (UTC)

Vee-tee-lee-go. It's Latin word, not English.--79.175.119.238 (talk) 10:16, 20 January 2011 (UTC)

source please[edit]

Where is the source for Eddie Panlilio having the disease? Its not even on his own wiki page —Preceding unsigned comment added by 68.32.31.254 (talk) 02:54, 3 August 2009 (UTC)

Chlorine version[edit]

My version. Vitiligo – is simply result of atomic chlorine, chlorine synthesis from salt anion into skin surface when water evaporate from skin with electrons - skin credit electrons process, skin debet plus charge and atomic chlorine process.

The main cause of Vitiligo is individual redundant electric plus charge of skin for individual chlorine minus anion concentration.

Less chlorine, less water evaporate = more air humidity with electrons ionization, don't live on west beach, live on east beach.

I have no Vitiligo but think that know why .. Earth rotate – electrons quick runs from west to east by the ground and slowly fly from east to west by air water steam. West beach have more plus charge after electrons runs to east and atomic chlorine (and oxygen) every day do erosion – Norwegian, New Zealand fiords, British Columbia and other. Excellent places of minus charge are all volcanos like Krakatau, may be.

Atomic oxygen can be created on anode too. All atmosphere oxygen is creating direct from water on west beach stones with plus charge, not from photosynthesis, atomic oxygen can be created direct into skin surface with plus charge. Stop plus charge = stop Vitiligo, may be.

Hard Sweden blondes are adapted for living on west beaches into active oxygen and chlorine atmosphere.

Zgrad (talk) 20:31, 6 August 2009 (UTC)

Misunderstanding vitiligo[edit]

I knew two people with vitiligo. They were both female and with parents, one of whom was Maori, and the other Scottish or Irish. One had her hands and feet affected, the other her whole body. I assumed for some time, that it was purely a genetic phenomenon, where the brown skin / white skin genomic determinants did not completely mesh to give an intermediate colour, but in some skin areas, the mother's or the father's genome took the forefront. (This sort of DNA affect DOES occur in other situations, but it is rare.) Now I realize the truth. The only reason I noticed vitiligo cases was because depigmentation is much more visible in people who have more melanin in their skin, that is, those who are black, brown or yellow skinned people. If Michael Jackson had been white, vitiligo would hardly have been the trauma that it was in his case. White people would be able to use cosmetics much more readily to disguise the effect. Incidentally, I don't regard the condition as being on a level of birthmarks as far as marring beauty goes. In fact, I think it can look quite sexy. But I guess I wouldn't want to have the condition, either. Myles325a (talk) 01:06, 28 September 2009 (UTC)

Comment RE: Addison's disease[edit]

Stated in this article is the following: "Addison's disease (typically an autoimmune destruction of the adrenal glands) may cause vitiligo.[7][8]". This is a careless statement and needs to be contended because if you click the link to read the Wiki article on Addison's disease, stated is the following: "Adrenal insufficiency is manifested in the skin primarily by hyperpigmentation.[5]:501. It is claimed that Addison's disease is a rare endocrine disorder wherein the adrenal glands produce insufficient(ly). So which is it? It can't cause Vitiligo AND hyperpigmentation. —Preceding unsigned comment added by 38.99.11.219 (talk) 00:17, 19 December 2009 (UTC)

Bhutto[edit]

The wrong daughter of Benazir Bhutto is listed. It's actually Asifa that has vitiligo actually. I'm going too change it but if anyone doesn't want me too, feel free too change it back :)

SashaJohn 23:28, 11 January 2010 (UTC)

Solution in Cuba?[edit]

This website claims they can solve the problem. http://www.cubaforhealth.com/eng/vitiligo.php Someone from my family wants to go there. I'm kind of skeptical. If they could do it, do they have any journal publication or something? --67.188.195.216 (talk) 06:39, 8 February 2010 (UTC)

External Review Comments[edit]

Hello, Vitiligo article writers and editors. This article currently a priority article for the Wikipedia talk:WikiProject Medicine/Google Project. The goal of this project to is provide a useful list of suggested revisions to help promote the expansion and improvement of this article.

BSW-RMH (talk) 19:00, 18 July 2010 (UTC)

Introduction[edit]

Overall, this article requires expansion to give a comprehensive overview of the Vitiligo. It currently states that certain theories are fact, particularly regarding the causes of Vitiligo, and omits other theories of equal weight.

The intro paragraph needs to be rewritten to reflect that the cause of Vitiligo is not known but research evidence suggests that the disorder may have from genetic, autoimmune, oxidative stress, neural, or viral causes.[1] I have rewritten the introduction to reflect this.

The statement about melanocytes arising from the neural crest seems misplaced and unnecessary in the introduction. I have removed it.

Green tickY BSW-RMH (talk) 19:00, 18 July 2010 (UTC)

Signs & symptoms[edit]

I’ve added additional citations to this section.

I removed the claim that, “Psychological stress may even result in an individual becoming more susceptible to vitiligo.” The evidence to support this is anecdotal and it would be misleading to claim it as fact.

It would be good to add that symptoms usually begin between ages 10 and 30 years.

symptoms of Vitiligo are:

  • whitening or graying of hair (Halder RM, et al. Vitiligo. In: Wolff K, et al. Fitzpatrick's Dermatology in General Medicine. 7th ed. New York, N.Y.: McGraw-Hill Professional; 2007.)
  • loss of skin color inside the mouth(What Is Vitiligo? Fast Facts, see previosu citation)
  • loss of eye color (Halder 2007, see previous citation)


The non-segmental classifications include the following classes of Vitiligo:

  • Generalized Vitiligo: the most common pattern, wide and randomly distributed areas of depigmentation (Halder 2007)
  • Universal Vitiligo: depigmentation encompasses most of the body (Halder 2007)
  • Focal Vitiligo: one or a few scattered macules in one area, most common in children (Halder 2007)
  • Acrofacial Vitiligo: fingers and periorificial areas (Halder 2007)
  • Muscosal Vitiligo: depigmentation of only the mucous membranes (Halder 2007)

A section of differential diagnosis could be added to list disorders with symptoms similar to Vitiligo including (Halder 2007):

BSW-RMH (talk) 01:42, 7 August 2010 (UTC)

Green tickY All of this information was added to the article. BSW-RMH (talk) 02:53, 12 August 2010 (UTC)

Pathogenesis[edit]

This section is too technically detailed and summarizes selected primary research articles. The detailed discussion of genetic studies is not useful and should be removed. Articles should be written for the average reader and jargon clearly explained, see Wikipedia:Manual of Style (medicine-related articles).

Instead, it should be rewritten to be a comprehensive overview of the theories of Vitiligo etiology, rather focusing on only the evidence for genetic and certain aspects of the autoimmune components of the disease. Useful references for this purpose are:

  • Halder RM, Chappell JL. Vitiligo update. Semin Cutan Med Surg. (2009);28(2):86-92. PMID: 19608058
  • Kakourou T. Vitiligo in children. World J Pediatr. (2009);5(4):265-8. Epub 2009 Nov 13.PMID: 19911140
  • Gawkrodger DJ. Vitiligo: what general physicians need to know. Clin Med. 2009 Oct;9(5):408-9. PMID: 19886094

BSW-RMH (talk) 19:00, 18 July 2010 (UTC)

Treatment[edit]

Green tickYI’ve removed the experimental/speculative treatment claims that do not have sufficient scientific/medical basis: Melangenina Plus, chickpeas, gingko bilboa, piperine. To include them here would be misleading.

The sections on sunscreen and cosmetic treatment are fine as is. However I would suggest revising the section according to this outline:

  • Topical creams & ointments
    • corticosteroids (
    • immunomodulators (tacrolimus, pimecrolimus)
    • depigmentation (hydroquinone, monobenzone)
  • Phototherapy: 8-methoxy psoralen combined with UVA irradiation

(PUVA)

  • Surgical options: skin grafts, blister grafting, tattooing

See:

  • Halder RM et al. (2007). "Vitiligo". In Wolff K et al.. Fitzpatrick's Dermatology in General Medicine (7th ed. ed.) (New York: McGraw-Hill Professional). 
  • Halder RM, Chappell JL (2009). "Vitiligo update". Semin Cutan Med Surg. 28 (2): 86–92. PMID 19608058. 
  • Whitton ME, Ashcroft DM, González U (2008). "Therapeutic interventions for vitiligo". Journal of the American Academy of Dermatology 59 (4): 713–7. PMID 18793940. 
  • Hossani-Madani AR, Halder RM (2010). "Topical treatment and combination approaches for vitiligo: new insights, new developments". G Ital Dermatol Venereol. 145 (1): 57–78. PMID 20197746. 
  • Holla AP, Parsad D (2010). "Vitiligo surgery: its evolution as a definite treatment in the stable vitiligo". G Ital Dermatol Venereol. 145 (1): 79–88. PMID 20197747. 
  • Whitton ME, Pinart M, Batchelor J, Lushey C, Leonardi-Bee J, González U (2010). "Interventions for vitiligo". Cochrane Database Syst Rev. 20 (1). PMID 20091542. CD003263. 
  • Lotti T, Berti S, Moretti S (2009). "Vitiligo therapy". Expert Opin Pharmacother. 10 (17): 2779–85. PMID 19929701. 

BSW-RMH (talk) 19:00, 18 July 2010 (UTC)

Reworked above to {{cite journal}} form. LeadSongDog come howl! 21:30, 21 July 2010 (UTC)

Notable Cases[edit]

Generally, lists like these should contain only figures that have contributed to the understanding and public understanding of the disease/disorder in question. However, Vitiligo has psychosocial implications because it affects skin color and an extensive list is therefore of public interest. I have removed unverified figures from the list.

BSW-RMH (talk) 19:00, 18 July 2010 (UTC)

apparantly 1 in 200 people suffer from it, including me http://www.netdoctor.co.uk/ate/skinandhair/204975.html —Preceding unsigned comment added by Andyjlaidlaw (talkcontribs) 22:34, 22 July 2010 (UTC)

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Edit of confusing parallelism[edit]

I edited from this: "the patches can be made less visible by avoiding sunlight and sun tanning of unaffected skin."

to this: "the patches can be made less visible by avoiding both sunlight and the tanning of unaffected skin."

I'm assuming this is the correct meaning intended. Note that the previous version could be interpreted as recomminding two actions:

1) Avoiding sunlight 2) Sun tanning of unaffected skin

This reading is tempting because "avoiding" and "sun tanning" are the starts of gerund phrases, connected by "and." Yet it seems illogical. If you choose to revert, be sure that you really intend for people to tan their unaffected skin areas.zadignose (talk) 07:31, 9 April 2012 (UTC)

Notable Case(s)[edit]

The "Notable Cases" section only lists one case. 75.118.51.238 (talk) 02:25, 12 September 2013 (UTC)

I added two new "Notable Cases" but I somehow ruined the formatting of the See More and Reflist and can't figure it out. Help? — Preceding unsigned comment added by 123.211.231.131 (talk) 12:40, 7 April 2014 (UTC)

notable cases[edit]

That photo looks like quite an old Michael Jackson so can it really be him in the early stages of the illness. And no one knows when he claimed to be in the early stages of the disease so it shouldn't really say that under the photo as it could be quite inaccurate. am changing it simply to photo of Michael Jackson Delighted eyes (talk) 12:07, 1 July 2014 (UTC)

Also the only citation for Michael Jackson is inaccurate does anyone have an accurate one Delighted eyes (talk) 12:23, 1 July 2014 (UTC)

  1. ^ Halder RM, Chappell JL. Vitiligo update. Semin Cutan Med Surg. (2009);28(2):86-92. PMID: 19608058