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Systematic (IUPAC) name
Clinical data
Legal status
CAS number 7182-51-6
ATC code None
PubChem CID 23573
ChemSpider 22042
UNII 5PY881HC79 YesY
Chemical data
Formula C20H25NO 
Molecular mass 295.42 g/mol

Talopram (Lu 3-010), also known as phthalapromine, is a selective norepinephrine reuptake inhibitor (NRI) which was researched for the management of depression in the 1960s and 1970s but was never commercialized. Along with talsupram, talopram is structurally related to the selective serotonin reuptake inhibitor (SSRI) citalopram,[1] as well as to melitracen:[2]

See also[edit]


  1. ^ Eildal, Jonas N. N.; Andersen, Jacob; Kristensen, Anders S.; Jørgensen, Anne Marie; Bang-Andersen, Benny; Jørgensen, Morten; Strømgaard, Kristian (2008). "From the Selective Serotonin Transporter Inhibitor Citalopram to the Selective Norepinephrine Transporter Inhibitor Talopram: Synthesis and Structure−Activity Relationship Studies". Journal of Medicinal Chemistry 51 (10): 3045–3048. doi:10.1021/jm701602g. PMID 18429609.  edit
  2. ^ http://www.healyprozac.com/Book/Introduction.pdf