The Tanggula is the source of the Ulan Moron and Dangqu Rivers, the geographic headwaters of the Yangtze. The range thus functions as a dividing range between the basin of the Yangtze River in the north and the endorheic basins of north-eastern Tibet in the south.
The elevations of the main ridge average more than 5,000 m (16,404 ft). The Yangtze River originates in this mountain range and Peak Geladandong (at 6,621 metres or 21,722 feet, located within the town of Tanggula) is the tallest peak in the range.
The Qinghai-Tibet Highway and the Qinghai-Tibet Railway cross the Tanggula Mountains at Tanggula Mountain Pass. This is the highest point of the Qinghai-Tibet Railway, and the highest point of any railway in the world, at 5,072 metres (16,640 feet) above sea level. On account of the snow and occasional road accidents, highway closures and concomitant traffic delays are not uncommon.
In Command & Conquer: Generals,A GLA toxin facility was established in this mountains,unable to use conventional weapons due to a severe consequences if it was destroyed by conventional means,except a firestorm can.a PLA Air Force airstrike failed to destroy it.A task force must eliminate the Stinger Sites first before another airstrike will be ordered.