Tariquidar

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Tariquidar
Tariquidar.png
Systematic (IUPAC) name
N-[2-[[4-[2-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]carbamoyl]-4,5-dimethoxyphenyl]quinoline-3-carboxamide
Clinical data
Legal status ?
Identifiers
CAS number 206873-63-4 YesY
ATC code None
PubChem CID 148201
UNII J58862DTVD YesY
ChEMBL CHEMBL348475 N
Chemical data
Formula C38H38N4O6 
Mol. mass 646.73 g/mol
 N (what is this?)  (verify)

Tariquidar (INN/USAN) is a P-glycoprotein inhibitor[1] undergoing research as an adjuvant against multidrug resistance in cancer.

References[edit]

  1. ^ Robey RW, Shukla S, Finley EM, Oldham RK, Barnett D, Ambudkar SV, Fojo T, Bates SE. Inhibition of P-glycoprotein (ABCB1)- and multidrug resistance-associated protein 1 (ABCC1)-mediated transport by the orally administered inhibitor, CBT-1((R)). Biochem Pharmacol 2008;3:1302-12. PMID 18234154.