Tefibazumab

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Tefibazumab ?
Monoclonal antibody
Type Whole antibody
Source Humanized (from mouse)
Target Clumping factor A
Clinical data
Pregnancy cat.  ?
Legal status  ?
Identifiers
CAS number 521079-87-8 N
ATC code None
KEGG D06054 YesY
Chemical data
Formula C6548H10122N1730O2034S44 
Mol. mass 147.590 kDa
 N (what is this?)  (verify)

Tefibazumab (marketed under the brand name Aurexis) is a humanized monoclonal antibody for the treatment of severe infections with Staphylococcus aureus. Possible indications include the treatment of S. aureus in patient with cystic fibrosis[1] and of methicillin-resistant S. aureus.[2]

It was developed by Inhibitex.[3]

[edit] See also

  • MSCRAMM (microbial surface components recognizing adhesive matrix molecules)

[edit] References

  1. ^ ClinicalTrials.gov NCT00198289
  2. ^ Pan; Lorenzotti, S.; Zoncada, A. (2008). "Registered and investigational drugs for the treatment of methicillin-resistant Staphylococcus aureus infection". Recent patents on anti-infective drug discovery 3 (1): 10–33. doi:10.2174/157489108783413173. PMID 18221183.  edit
  3. ^ John JF (2006). "Drug evaluation: tefibazumab--a monoclonal antibody against staphylococcal infection". Curr. Opin. Mol. Ther. 8 (5): 455–60. PMID 17078388. 


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