Tegafur

Tegafur

Systematic (IUPAC) name
(RS)-5-Fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy cat.	?
Legal status	℞ Prescription only
Routes	Oral
Identifiers
CAS number	17902-23-7 Y
ATC code	L01BC03
PubChem	CID 288216
ChemSpider	254191 Y
UNII	1548R74NSZ Y
KEGG	D01244 Y
ChEMBL	CHEMBL20883 N
Synonyms	5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
Chemical data
Formula	C8H9FN2O3
Mol. mass	200.16 g/mol
SMILES FC=1C(=O)NC(=O)N(C=1)[C@@H]2OCCC2
InChI InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13)/t6-/m1/s1 Y Key:WFWLQNSHRPWKFK-ZCFIWIBFSA-N Y
N (what is this?)  (verify)

Tegafur (INN) is a chemotherapeutic fluorouracil prodrug used in the treatment of cancers. It is a component of the combination drug tegafur-uracil. When metabolized, it becomes 5-fluorouracil.

Interactive pathway map

Click on genes, proteins and metabolites below to link to respective articles.

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Fluorouracil (5-FU) Activity edit