Teklanika River Valley in Denali National Park and Preserve
|Districts||Denali Borough, Yukon–Koyukuk Census Area|
|Source||Cantwell Glacier in Denali National Park|
|- location||Alaska Range, Denali Borough|
|- elevation||4,370 ft (1,332 m) |
|Mouth||Nenana River |
|- location||10 miles (16 km) southwest of Nenana, Yukon–Koyukuk Census Area|
|- elevation||413 ft (126 m) |
|Length||90 mi (145 km) |
The Teklanika River is a 91-mile (146 km) tributary of the Nenana River in the U.S. state of Alaska. The Nenana is a tributary of the Tanana River, which is part of the Yukon River drainage in the central interior region of the state. Flowing northward from headwaters at the Cantwell Glacier in the Alaska Range, the Teklanika drains an area widely visited by tourists to Denali National Park and Preserve. The park's only road crosses the river at milepost 31 and a National Park campground is located on its eastern bank at milepost 29.
On its course, the river travels north from the core Alaska Range as a braided river, becoming rapid and narrow as it traverses through the Primrose Ridge, braiding again through the Stampede Trail valley, narrowing again through the Tekla Ridge before ultimately meandering through a complex series of oxbow turns and lakes across the southern Tanana River valley.
In the book Into the Wild, the Teklanika River is referred to as the Rubicon for American adventurer Christopher McCandless. Since then, the river has proven an obstacle to many hikers attempting to reach the bus where McCandless lived and died.
In August 2010, Swiss hiker, Claire Ackermann drowned in an attempt to cross the river while tied off to a rope that was strung by previous hikers between trees on both shores. While she drowned on state land, her body was pulled ashore by a French traveling buddy a short distance downriver. That point was on Denali National Park land, triggering a dispute between Park Rangers and State Troopers as to jurisdiction. 
- Derived by entering source coordinates in Google Earth.
- "Teklanika River". Geographic Names Information System. United States Geological Survey. March 31, 1981. Retrieved October 23, 2013.
- Alaska Atlas & Gazetteer (7th ed.). Yarmouth, Maine: DeLorme. 2010. pp. 104, 114, 122. ISBN 978-0-89933-289-5.
- Bright, William (2004). Native American Place Names of the United States. Norman: University of Oklahoma Press. p. 486. ISBN 0-8061-3576-X.