Telogen effluvium

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Telogen effluvium
Classification and external resources
Malnurished Afghan Child.jpg
An Afghan child displaying hair loss due to severe malnutrition.
ICD-10 L65.0 (ILDS L65.000)
ICD-9 704.02
DiseasesDB 12926

Telogen effluvium is a scalp disorder characterized by the thinning or shedding of hair resulting from the early entry of hair in the telogen phase (the resting phase of the hair follicle).[1][2] Emotional or physiological stress may result in an alteration of the normal hair cycle and cause the disorder, with potential etiologies including eating disorders, fever, childbirth, chronic illness, major surgery, anemia, severe emotional disorders, crash diets, hypothyroidism, and drugs.[1][3]

Diagnostic tests, which may be performed to verify the diagnosis, include a trichogram, trichoscopy[4] and biopsy.[3] Effluvium can present with similar appearance to alopecia totalis, with further distinction by clinical course, microscopic examination of plucked follicles, or biopsy of the scalp.[5] Histology would show telogen hair follicles in the dermis with minimal inflammation in effluvium, and dense peribulbar lymphocytic infiltrate in alopecia totalis.[6]

See also[edit]

Vitamin D levels may also play a role in normal hair cycle. [7]

References[edit]

  1. ^ a b Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 263. ISBN 1-4160-3185-5.
  2. ^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.
  3. ^ a b Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0-07-138076-0.
  4. ^ Rudnicka L, Olszewska M, Rakowska A, Kowalska-Oledzka E, Slowinska M. (2008). "Trichoscopy: a new method for diagnosing hair loss". J Drugs Dermatol 7 (7): 651–654. PMID 18664157. 
  5. ^ Werner, B.; Mulinari-Brenner, F. (2012). "Clinical and histological challenge in the differential diagnosis of diffuse alopecia: Female androgenetic alopecia, telogen effluvium and alopecia areata - part II". Anais brasileiros de dermatologia 87 (6): 884–890. PMID 23197208.  edit
  6. ^ Alkhalifah, A. (2012). "Alopecia Areata Update". Dermatologic Clinics 31 (1): 93–108. doi:10.1016/j.det.2012.08.010. PMID 23159179.  edit
  7. ^ Does D matter? The role of vitamin D in hair disorders and hair follicle cycling. Dermatol Online J. 2010 Feb; 16(2). PMID 20178699