Template:Bleeding worksheet

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Laboratory findings in various platelet and coagulation disorders (V - T)
Condition Prothrombin time Partial thromboplastin time Bleeding time Platelet count
Vitamin K deficiency or warfarin Prolonged Normal or mildly prolonged Unaffected Unaffected
Disseminated intravascular coagulation Prolonged Prolonged Prolonged Decreased
Von Willebrand disease Unaffected Prolonged or unaffected Prolonged Unaffected
Hemophilia Unaffected Prolonged Prolonged Unaffected
Aspirin Unaffected Unaffected Prolonged Unaffected
Thrombocytopenia Unaffected Unaffected Prolonged Decreased
Liver failure, early Prolonged Unaffected Unaffected Unaffected
Liver failure, end-stage Prolonged Prolonged Prolonged Decreased
Uremia Unaffected Unaffected Prolonged Unaffected
Congenital afibrinogenemia Prolonged Prolonged Prolonged Unaffected
Factor V deficiency Prolonged Prolonged Unaffected Unaffected
Factor X deficiency as seen in amyloid purpura Prolonged Prolonged Unaffected Unaffected
Glanzmann's thrombasthenia Unaffected Unaffected Prolonged Unaffected
Bernard-Soulier syndrome Unaffected Unaffected Prolonged Decreased or unaffected
Factor XII deficiency Unaffected Prolonged Unaffected Unaffected
C1INH deficiency Unaffected Shortened Unaffected Unaffected

Notes[edit]

Platelet count in Bernard-Soulier syndrome[edit]

Platelet count in Bernard-Soulier syndrome
Source Quote from source
Hillman[1] normal to slightly reduced platelet count (page 389)
McPhee[2] moderate thrombocytopenia (page 530)
Hoffbrand[3] variable degree of thrombocytopenia (page 341)
Kaplan[4] "unaffected" (as reported by WP editor Jabway, citing page 254)
Lanza[5] low platelet counts

References[edit]

  1. ^ Hillman RS, Ault KA, Leporrier M, Rinder HM. (2011; edition 5.) Hematology in Clinical Practice. McGraw-Hill. ISBN 978-0-07-162699-6.
  2. ^ McPhee SJ, Papadakis M. (2012; edition 51.) Current Medical Diagnosis & Treatment. McGraw-Hill. ISBN 978-0-07-176372-1.
  3. ^ Hoffbrand AV, Moss PAH (2011). Essential Haematology.(edition 6). Wiley-Blackwell. ISBN 978-1-4051-9890-5. 
  4. ^ Kaplan QBook - USMLE Step 1 October 4, 2011 5th edition ISBN 978-1609782245
  5. ^ Lanza F (2006). "Bernard-Soulier syndrome (hemorrhagiparous thrombocytic dystrophy)". Orphanet J Rare Dis. 16 (1): 46. doi:10.1186/1750-1172-1-46. PMC 1660532. PMID 17109744.