Template:PBB/1543

Cytochrome P450, family 1, subfamily A, polypeptide 1
Available structures PDB Ortholog search: PDBe, RCSB List of PDB id codes 4I8V
Identifiers
Symbols	CYP1A1; AHH; AHRR; CP11; CYP1; P1-450; P450-C; P450DX
External IDs	OMIM: 108330 MGI: 88588 HomoloGene: 68062 ChEMBL: 2231 GeneCards: CYP1A1 Gene
EC number	1.14.14.1
Gene Ontology Molecular function • iron ion binding • steroid hydroxylase activity • electron carrier activity • oxidoreductase activity • oxidoreductase activity, acting on diphenols and related substances as donors • flavonoid 3'-monooxygenase activity • oxygen binding • enzyme binding • heme binding • demethylase activity • aromatase activity • vitamin D 24-hydroxylase activity Cellular component • mitochondrion • endoplasmic reticulum membrane Biological process • response to hypoxia • porphyrin-containing compound metabolic process • xenobiotic metabolic process • aging • cell proliferation • amine metabolic process • response to wounding • response to virus • response to nematode • response to herbicide • embryo development ending in birth or egg hatching • coumarin metabolic process • flavonoid metabolic process • response to iron(III) ion • response to organic cyclic compound • insecticide metabolic process • drug metabolic process • dibenzo-p-dioxin catabolic process • arachidonic acid metabolic process • epoxygenase P450 pathway • response to food • response to lipopolysaccharide • response to vitamin A • vitamin D metabolic process • response to drug • 9-cis-retinoic acid biosynthetic process • camera-type eye development • cellular lipid metabolic process • small molecule metabolic process • positive regulation of S phase of mitotic cell cycle • response to antibiotic • response to arsenic-containing substance • digestive tract development • hydrogen peroxide biosynthetic process • response to hyperoxia • oxidation-reduction process • maternal process involved in parturition • hepatocyte differentiation • omega-hydroxylase P450 pathway Sources: Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	1543	13076
Ensembl	ENSG00000140465	ENSMUSG00000032315
UniProt	P04798	P00184
RefSeq (mRNA)	NM_000499	NM_001136059
RefSeq (protein)	NP_000490	NP_001129531
Location (UCSC)	Chr 15: 75.01 – 75.02 Mb	Chr 9: 57.7 – 57.7 Mb
PubMed search	[1]	[2]