Template:PBB/1956

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Epidermal growth factor receptor
1NQL.png
Extracellular domain of Epidermal growth factor receptor in complex with EGF. PDB 1nql[1]
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols EGFR ; ERBB; ERBB1; HER1; PIG61; mENA
External IDs OMIM131550 MGI95294 HomoloGene74545 ChEMBL: 203 GeneCards: EGFR Gene
EC number 2.7.10.1
RNA expression pattern
PBB GE EGFR 201983 s at.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 1956 13649
Ensembl ENSG00000146648 ENSMUSG00000020122
UniProt P00533 Q01279
RefSeq (mRNA) NM_005228 NM_007912
RefSeq (protein) NP_005219 NP_031938
Location (UCSC) Chr 7:
55.09 – 55.32 Mb
Chr 11:
16.75 – 16.92 Mb
PubMed search [1] [2]
  1. ^ Ferguson KM, Berger MB, Mendrola JM, Cho HS, Leahy DJ, Lemmon MA (2003). "EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization". Mol. Cell 11 (2): 507–17. doi:10.1016/S1097-2765(03)00047-9. PMID 12620237.