Template:PBB/5243

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ATP-binding cassette, sub-family B (MDR/TAP), member 1
MDR3 3g5u.png
Crystallographic structure of the mouse MDR3 protein. The approximate positioning of the protein in the cell membrane is indicated by the blue (extracellular face) and red (cytoplasmic face) lines. The protein is depicted as a rainbow colored cartoon (N-terminus = blue, C-terminus = red). A cyclic peptide inhibitor QZ59 is represented by a space-filling model.[1]
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ABCB1 ; ABC20; CD243; CLCS; GP170; MDR1; P-GP; PGY1
External IDs OMIM171050 MGI97570 HomoloGene55496 ChEMBL: 4302 GeneCards: ABCB1 Gene
EC number 3.6.3.44
RNA expression pattern
PBB GE ABCB1 209994 s at tn.png
PBB GE ABCB1 209993 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 5243 18671
Ensembl ENSG00000085563 ENSMUSG00000040584
UniProt P08183 P21447
RefSeq (mRNA) NM_000927 NM_011076
RefSeq (protein) NP_000918 NP_035206
Location (UCSC) Chr 7:
87.13 – 87.34 Mb
Chr 5:
8.66 – 8.75 Mb
PubMed search [1] [2]

References

These references will appear in the article, but this list appears only on this page.
  1. ^ PDB 3G60; Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G (March 2009). "Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding". Science 323 (5922): 1718–22. doi:10.1126/science.1168750. PMC 2720052. PMID 19325113.