Tertatolol

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Tertatolol
Tertatolol.svg
Systematic (IUPAC) name
(±)-1-(tert-Butylamino)-3-(3,4-dihydro-2H-thiochromen-8-yloxy)propan-2-ol
Clinical data
AHFS/Drugs.com International Drug Names
  • (Prescription only)
Oral
Identifiers
34784-64-0 YesY
C07AA16
PubChem CID 36920
IUPHAR ligand 571
ChemSpider 33875 N
UNII 9ZO341YQXP N
KEGG D07182 YesY
ChEMBL CHEMBL434200 N
Chemical data
Formula C16H25NO2S
295.44 g/mol
 N (what is this?)  (verify)

Tertatolol (Artex, Artexal, Prenalex) is a medication in the class of beta blockers, used in the treatment of high blood pressure. It was discovered by the French pharmaceutical company Servier and is marketed in Europe.[1]

Tertatolol has also been shown to act as a 5-HT1A receptor antagonist, similarly to pindolol.[2][3]

See also[edit]

References[edit]

  1. ^ Swiss Pharmaceutical Society (2000). Index Nominum 2000: International Drug Directory (Book with CD-ROM). Boca Raton: Medpharm Scientific Publishers. ISBN 3-88763-075-0. 
  2. ^ Jolas T, Haj-Dahmane S, Lanfumey L et al. (May 1993). "(-)Tertatolol is a potent antagonist at pre- and postsynaptic serotonin 5-HT1A receptors in the rat brain". Naunyn-Schmiedeberg's Archives of Pharmacology 347 (5): 453–63. doi:10.1007/bf00166735. PMID 7686633. 
  3. ^ Soudijn, W.; Olivier, Berend; Wijngaarden, I. van (1997). Serotonin receptors and their ligands. Amsterdam: Elsevier. ISBN 0-444-82041-8.