|Systematic (IUPAC) name|
|Mol. mass||300.43 g/mol|
|(what is this?)|
Tetrahydrocannabinol-C4, also known as THC-C4 and butyl-THC, is a homologue of tetrahydrocannabinol (THC), the active component of Cannabis. They are only different by the pentyl sidechain being replaced by a butyl sidechain. It is unknown whether THC-C4 is an agonist, partial agonist, or antagonist at the cannabinoid receptors. The propyl anolog, THCV is a known antagonist while THC itself is an agonist. THC-C4 has rarely been isolated from cannabis samples, but appears to be less commonly present than THC or THCV. It is metabolised in a similar manner to THC. Similarly to THC, it has 7 double bond isomers and 30 stereoisomers.
It is not scheduled by Convention on Psychotropic Substances.
- Harvey DJ. Characterization of the butyl homologues of delta1-tetrahydrocannabinol, cannabinol and cannabidiol in samples of cannabis by combined gas chromatography and mass spectrometry. Journal of Pharmacy and Pharmacology. 1976 Apr;28(4):280-5. PMID 6715
- Brown NK, Harvey DJ. In vivo metabolism of the n-butyl-homologues of delta 9-tetrahydrocannabinol and delta 8-tetrahydrocannabinol by the mouse. Xenobiotica. 1988 Apr;18(4):417-27. PMID 2840781
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