The storyline of the game follows the contemporary comic book storyline that was being published at the same time; Spider-Man is being attacked by an assortment of high-tech robot Spider-Slayers.
As was the case with Spider-Man 2, the player had to control Spider-Man through various levels, fighting enemies and super villains while also trying to solve various types of puzzles, i.e. the first level the player had to distinguish between criminals in the park and men just reading a newspaper in the park. Then after defeating enough real thugs, the player had to manage several tricky web swings in order to get to the top of a building.
As was the case with The Amazing Spider-Man 2, critics generally panned the game as having small graphics, complicated controls, grammatical errors in the exposition scenes, and being frustratingly difficult.