The Big C

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The Big C may refer to:

  • The Big C (TV series), a Showtime original series starring Laura Linney
  • The Big "C", a concrete block of the letter "C" overlooking the University of California, Berkeley
  • A euphemism for cancer, a class of diseases involving a malignant and invasive growth or tumor
  • Chris Hardwick, host of The Nerdist Podcast