The brewpub is located at 3525 Liberty Avenue in the Lawrenceville neighborhood of Pittsburgh, Pennsylvania. The church building was originally built in 1902, and had been used as a church until 1993. Its doors opened as The Church Brew Works on August 1, 1996, after the building underwent extensive renovation, necessitated by years of lying dormant after being officially deconsecrated by the Diocese of Pittsburgh in 1993.
As of September 2007, three flagship brews are locally distributed: Celestial Gold (light lager), Pipe Organ Pale Ale (English pale ale), and Pious Monk Dunkel (Munich-style dark lager). The in-house selection is rounded out by a rotating Stout, four seasonals or specialties, and one varying cask-conditioned ale. Also available are Millennium Trippel, a Belgian Tripel (in champagne bottles and 5L minikegs) and Cherry Quadzilla, a Belgian Quadrupel (champagne bottles only).
The Church's beers are brewed on a steam-jacketed 15bbl system built by Specific Mechanical Systems, Ltd. of Victoria, British Columbia.