Toshiro Mifune plays Dr. Kyoji Fujisaki a young idealistic doctor who works at his father's (Takashi Shimura) clinic in a small and seedy district. During the war, he contracts syphilis from the blood of a patient (Kenjiro Uemura) when he cuts himself during an operation. Contaminated with a disease that was virtually incurable in 1940s Japan, Fujisaki returns home from the war to the clinic presided over by his obstetrician father. Treating himself in secret and tormented by his conscience, he rejects his heartbroken fiancée Misao,(Miki Sanjō) without explanation. He had been engaged to Misao for six years but has still not set a date due to a very good reason. During the war, Kyoji was working at a field hospital when he contracted syphilis from a patient(Kenjiro Uemura) during surgery and has kept it a secret from everybody until now. However, that changes when Minegishi(Noriko Sengoku), a probationary nurse that he took in after he prevented her suicide attempt, walks in on him as he is injecting himself.
The Quiet Duel was released on DVD in the US by BCI Eclipse, as the first title in their "Director's Series". It was never released in UK cinemas but was released on DVD in 2006 under the title of "The Silent Duel".