Thecomas or theca cell tumors are benign ovarian neoplasms composed only of theca cells. Histogenetically they are classified as sex cord-stromal tumours.
They are typically estrogen-producing and they occur in older women (mean age 59; 84% after menopause). (They can, however, appear before menopause.)
Sixty percent of patients present with abnormal uterine bleeding, and 20% have endometrial carcinoma.
Low magnification micrograph of a thecoma
showing compression of the ovarian cortex (right of image). H&E stain
Grossly, the tumour is solid and yellow.
Grossly and microscopically, it consists of the ovarian cortex.
Microscopically, the tumour cells have abundant lipid-filled cytoplasm.